ROCK1-IN-1
Based on 1 publication(s) in Google Scholar
ROCK1-IN-1 is a potent selective ROCK1 inhibitor with a Ki of 540 nM. ROCK1-IN-1 can be used for the research of hypertension.
For research use only. We do not sell to patients.
- Purity: 99.14%
- CAS No.: 692869-38-8
- Formula: C17H15N3O2S
- Molecular Weight:325.39
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) ROCK1-IN-1
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Biological Activity
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ROCK1 450 nM (Ki) |
Chemical Information
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CAS No. 692869-38-8
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Appearance Solid
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Molecular Weight 325.39
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Formula C17H15N3O2S
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Color Off-white to light yellow
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SMILES
O=C(NC1=NC(C2=CC=NC=C2)=CS1)CC3=CC=C(OC)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
Solvent & Solubility
DMSO : 125 mg/mL (384.15 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0732 mL | 15.3662 mL | 30.7324 mL | 76.8309 mL |
| 5 mM | 0.6146 mL | 3.0732 mL | 6.1465 mL | 15.3662 mL | |
| 10 mM | 0.3073 mL | 1.5366 mL | 3.0732 mL | 7.6831 mL | |
| 15 mM | 0.2049 mL | 1.0244 mL | 2.0488 mL | 5.1221 mL | |
| 20 mM | 0.1537 mL | 0.7683 mL | 1.5366 mL | 3.8415 mL | |
| 25 mM | 0.1229 mL | 0.6146 mL | 1.2293 mL | 3.0732 mL | |
| 30 mM | 0.1024 mL | 0.5122 mL | 1.0244 mL | 2.5610 mL | |
| 40 mM | 0.0768 mL | 0.3842 mL | 0.7683 mL | 1.9208 mL | |
| 50 mM | 0.0615 mL | 0.3073 mL | 0.6146 mL | 1.5366 mL | |
| 60 mM | 0.0512 mL | 0.2561 mL | 0.5122 mL | 1.2805 mL | |
| 80 mM | 0.0384 mL | 0.1921 mL | 0.3842 mL | 0.9604 mL | |
| 100 mM | 0.0307 mL | 0.1537 mL | 0.3073 mL | 0.7683 mL |
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