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Results for "

Tris group

" in MedChemExpress (MCE) Product Catalog:

27

Inhibitors & Agonists

4

Biochemical Assay Reagents

6

Click Chemistry

5

Oligonucleotides

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100138
    2-Aminoethyl-mono-amide-DOTA-tris(tBu ester)

    		Radionuclide-Drug Conjugates (RDCs) ADC Linker Cancer
    2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) is a metal chelator precursor containing a DOTA macrocyclic structure. DOTA can form highly stable complexes with metal ions (such as 68Ga, 177Lu) through four nitrogen atoms and four carboxylic acid groups to mediate targeted delivery of radionuclides. The tert-butyl ester group (tBu ester) of 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) also protects the carboxylic acid group during synthesis, and forms a free carboxyl group after deprotection reaction for coupling with targeting molecules (such as antibodies, peptides). 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) may be combined with tumor pre-targeting systems through bioorthogonal reactions (such as reverse electron demand Diels-Alder reaction) to study radioactive imaging or therapy of tumor tissues, and is mainly used in tumor pre-targeting research in the field of nuclear medicine .
    2-Aminoethyl-mono-amide-DOTA-tris(tBu ester)
  • HY-D0878
    TAPSO

    		Biochemical Assay Reagents Others
    TAPSO is a commonly used biological buffer and pH-stabilizing reagent, with an effective pH range of 7-8 and a pKa range of 7.5-9. TAPSO contains a Tris group, exhibits considerable reactivity, and can interact with zwitterionic glycine peptides .
    TAPSO
  • HY-141253
    N-Boc-Tris

    		Biochemical Assay Reagents Others
    N-Boc-Tris is a protective reagent. N-Boc-Tris can utilize the Boc protecting group to protect amino groups in fields such as organic synthesis and pharmaceutical research and development, thereby avoiding unnecessary side reactions.
    N-Boc-Tris
  • HY-140523
    Azido-PEG4-amido-tri-(carboxyethoxymethyl)-methane

    		PROTAC Linkers Cancer
    Azido-PEG4-amido-tri-(carboxyethoxymethyl)-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-amido-tri-(carboxyethoxymethyl)-methane is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Azido-PEG4-amido-tri-(carboxyethoxymethyl)-methane
  • HY-W013156
    2′,3′,5′-Triacetylinosine

    2′,3′,5′-Tri-O-acetylinosine

    		 Biochemical Assay Reagents Cancer
    2′,3′,5′-Triacetylinosine (2′,3′,5′-Tri-O-acetylinosine) has been shown to inhibit the growth of cancer cells, and is also an efficient method for bond cleavage and radiation protection. 2',3',5'-Tri-O-acetylinosine has been shown to bind to pyridinium ions, and it has been used in the synthesis of tetrapeptides with hydroxyl groups or alkylation.
    2′,3′,5′-Triacetylinosine
  • HY-175412
    DDTAC

    Dodecylmercapto-S-(poly(Tris(hydroxymethyl)acrylamidomethane); H12-TAC

    		 Biochemical Assay Reagents Others
    DDTAC (H12-TAC) is a detergent that can extract and solubilize membrane proteins. DDTAC has a thio dodecanoyl chain linked to a polar group made of Tris polyalcoholic moieties and can be utilized in extracting yeast ATP synthase from mitochondrial membranes .
    DDTAC
  • HY-W190935
    Tris(O-TBDMS)3

    		Biochemical Assay Reagents Others
    Tris (O-TBDMS)3 is a Tris linker with 3 TBDMS protecting groups. The TBDMS is an acid labile protecting group.
    Tris(O-TBDMS)3
  • HY-W440682
    C13-113-tri-tail

    		Liposome Others
    C13-113-tri tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a tertiary amine linker. C13-113-tri tail can be formulated into a lipid nanoparticle (LNP).
    C13-113-tri-tail
  • HY-141249
    Azido-PEG4-Amido-Tris

    		PROTAC Linkers Cancer
    Azido-PEG4-Amido-Tris is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-Amido-Tris is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Azido-PEG4-Amido-Tris
  • HY-W440681
    C13-112-tri-tail

    		Liposome Others
    C13-112-tri-tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tri-tail can be formulated into a lipid nanoparticle (LNP).
    C13-112-tri-tail
  • HY-161436
    TPA-dT

    		Small Interfering RNA (siRNA) Others
    TPA-dT is a thymidine analog with a tris[(2-pyridyl)methyl]amine (TPA) group. TPA-dT can be used to modify siRNAs. The TPA-modified siRNAs remain functionally inactive and is incapable of silencing gene expression until the TPA moiety is removed upon exposure to Cu(I) .
    TPA-dT
  • HY-140874
    Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane

    		PROTAC Linkers Cancer
    Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane
  • HY-W190958
    Boc-NH-Tri-(carbonylethoxymethyl)-methane

    		Biochemical Assay Reagents Others
    Boc-NH-Tri-(carbonylethoxymethyl)-methane is a branched PEG linker with a Boc-protected amino and three terminal carboxilic acid groups. The Boc group can be deprotected under mild acidic conditions to form the free amine. The terminal carboxylic acid groups can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
    Boc-NH-Tri-(carbonylethoxymethyl)-methane
  • HY-154461
    5-Azidomethyl-2’,3’,5’-tri-O-benzoyl uridine

    		Nucleoside Antimetabolite/Analog Cancer
    5-Azidomethyl-2’,3’,5’-tri-O-benzoyl uridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis . 5-Azidomethyl-2’,3’,5’-tri-O-benzoyl uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    5-Azidomethyl-2’,3’,5’-tri-O-benzoyl uridine
  • HY-154462
    5-Azidomethyl-2’-beta-methyl-2’,3’,5’-tri-O-benzoyluridine

    		Nucleoside Antimetabolite/Analog Cancer
    5-Azidomethyl-2’-beta-methyl-2’,3’,5’-tri-O-benzoyluridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis . 5-Azidomethyl-2’-beta-methyl-2’,3’,5’-tri-O-benzoyluridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    5-Azidomethyl-2’-beta-methyl-2’,3’,5’-tri-O-benzoyluridine
  • HY-W009330
    TAPSO sodium

    		Biochemical Assay Reagents Others
    TAPSO sodium is a commonly used biological buffer and pH-stabilizing reagent, with an effective pH range of 7-8 and a pKa range of 7.5-9. TAPSO sodium contains a Tris group, exhibits considerable reactivity, and can interact with zwitterionic glycine peptides .
    TAPSO sodium
  • HY-W800846
    Fmoc-Amido-Tri-(carboxyethoxymethyl)-methane

    		Biochemical Assay Reagents Others
    Fmoc-Amido-Tri-(carboxyethoxymethyl)-methane is a multifunctional reagent containing three carboxylic acids and a primary amine that is Fmoc-protected. The carboxylic acids can react with primary amine groups to form stable amide bonds. The Fmoc protecting group can be removed using piperidine, freeing up the amine for a variety of uses such as coupling with carboxylic acids to form amide bonds.
    Fmoc-Amido-Tri-(carboxyethoxymethyl)-methane
  • HY-44312
    Cbz-TRIS tri-acid

    		Biochemical Assay Reagents Others
    Cbz-TRIS tri-acid is a small molecule compound containing several functional groups, including a carbamate group, a tris group, and three carboxylic acid groups.
    Cbz-TRIS tri-acid
  • HY-W1119955
    Cbz-TRIS-PDA trihydrochloride

    		Nucleoside Antimetabolite/Analog Others
    Cbz-TRIS-PDA (trihydrochloride) is a trifunctional compound containing a Cbz protecting group, which can be used in oligonucleotide synthesis.
    Cbz-TRIS-PDA trihydrochloride
  • HY-W800716
    Tri(Azide-PEG10-NHCO-ethyloxyethyl)amine

    		Biochemical Assay Reagents Others
    Tri(Azide-PEG10-NHCO-ethyloxyethyl)amine is a branched PEG linker with three terminal azide groups. The azide groups enable PEGylation via Click Chemistry.
    Tri(Azide-PEG10-NHCO-ethyloxyethyl)amine
  • HY-100138R
    2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) (Standard)

    		Radionuclide-Drug Conjugates (RDCs) ADC Linker Reference Standards Cancer
    2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) (Standard) is the analytical standard of 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) (HY-100138). This product is intended for research and analytical applications. 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) is a metal chelator precursor containing a DOTA macrocyclic structure. DOTA can form highly stable complexes with metal ions (such as 68Ga, 177Lu) through four nitrogen atoms and four carboxylic acid groups to mediate targeted delivery of radionuclides. The tert-butyl ester group (tBu ester) of 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) also protects the carboxylic acid group during synthesis, and forms a free carboxyl group after deprotection reaction for coupling with targeting molecules (such as antibodies, peptides). 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) may be combined with tumor pre-targeting systems through bioorthogonal reactions (such as reverse electron demand Diels-Alder reaction) to study radioactive imaging or therapy of tumor tissues, and is mainly used in tumor pre-targeting research in the field of nuclear medicine .
    2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) (Standard)
  • HY-186088
    DOTA-tris(t-Bu)ester-PEG3-C2-amine

    		Drug Intermediate Others
    DOTA-tris (t-Bu) ester-PEG3-C2-amine (Compound 9) is a conjugate of DOTA-based chelator and linker, bearing tris (t-Bu) ester and PEG3-C2-amine functional groups. DOTA-tris (t-Bu) ester-PEG3-C2-amine can be conjugated to payloads via bioorthogonal click chemistry for targeted delivery .
    DOTA-tris(t-Bu)ester-PEG3-C2-amine
  • HY-W800688
    Acid-PEG5-Amide-Tri (3-methoxypropanamide-PEG4-Azide) Methane

    		Biochemical Assay Reagents Others
    Acid-PEG5-Amide-Tri(3-methoxypropanamide-PEG4-Azide) Methane is a branched PEG linker with a terminal carboxylic acid group and three terminal azides. The azide groups enables PEGylation via Click Chemistry.
    Acid-PEG5-Amide-Tri (3-methoxypropanamide-PEG4-Azide) Methane
  • HY-W800715
    (Acid-PEG10)-Tri-(Azide-PEG10-ethoxymethyl)-methane

    		Biochemical Assay Reagents Others
    (Acid-PEG10)-Tri-(Azide-PEG10-ethoxymethyl)-methane can undergo Click Chemistry with Propargyl, BCN or DBCO reagents. Carboxylic acid (CO2H) group is reactive with primary amino groups in the presence of EDCor HATU.
    (Acid-PEG10)-Tri-(Azide-PEG10-ethoxymethyl)-methane
  • HY-W800706
    Azidobutanamide-tri-(carboxyethoxymethyl)-methane

    		Biochemical Assay Reagents Others
    Azidobutanamide-tri-(carboxyethoxymethyl)-methane is a aqueous soluble PEG linker with an azide group with three terminal carboxylic acids. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
    Azidobutanamide-tri-(carboxyethoxymethyl)-methane
  • HY-145973B
    3'OMe-m7GpppAmpG Tris

    		Nucleoside Antimetabolite/Analog SARS-CoV Infection
    3'OMe-m7GpppAmpG (Tris) is a trinucleotide Cap1 analog with the structure m7 (3'OMeG)(5') ppp (5')(2'OMeA) pG, and also functions as a cis-acting ligase ribozyme inhibitor. 3'OMe-m7GpppAmpG (Tris) effectively reduces free 5'-triphosphate groups on RNA transcripts, thereby enabling efficient co-transcriptional capping of in vitro transcribed mRNA. 3'OMe-m7GpppAmpG (Tris) is not only widely used in the preparation of modified mRNA including trivalent influenza vaccine candidates, but also applicable to studies related to SARS-CoV-2 infection and other relevant research .
    3'OMe-m7GpppAmpG Tris
  • HY-W800718
    Methyltetrazine-amido-Tri-(acid-PEG1-ethoxymethyl)-methane

    		Biochemical Assay Reagents Others
    Methyltetrazine-amido-Tri-(acid-PEG1-ethoxymethyl)-methane is a click chemistry PEG reagent which contains three carboxylic acid groups and a methyltetrazine group. This reagent can react with TCO-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
    Methyltetrazine-amido-Tri-(acid-PEG1-ethoxymethyl)-methane

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