11 Results for "

cGMP analogue

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "cGMP analogue" in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-101379A
CAS No.: 51116-01-9
Purity:  99.81%
8-Bromo-cGMP sodium, a membrane-permeable analogue of cGMP, is a PKG (protein kinase G) activator. 8-Bromo-cGMP sodium significantly inhibits Ca 2+ macroscopic currents and impairs insulin release stimulated with high K + . 8-Bromo-cGMP sodium has antinociceptive effects and results in vasodilator responses .
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2
2 Cited Publications
Cat. No.: HY-130354
CAS No.: 51116-00-8
Purity:  99.55%
Synonyms: Bt2cGMP sodium
Target:  

Potassium Channel

Research Areas:  

Cardiovascular Disease

Dibutyryl-cGMP sodium (Bt2cGMP sodium) is a cell-permeable cGMP analogue. Dibutyryl-cGMP sodium preferentially activates cGMP-dependent protein kinase (PKG). Dibutyryl-cGMP sodium inhibits the release of [ 3H]-arachidonic acid from γ thrombin-stimulated human platelets. Dibutyryl-cGMP sodium induces peripheral antinociception via activation of ATP-sensitive K + channels .
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Cat. No.: HY-108741
CAS No.: 467426-54-6
Purity:  99.93%
Target:  

Guanylate Cyclase

Research Areas:  

Inflammation/Immunology Cancer

Plecanatide, an analogue of Uroguanylin, is an orally active guanylate cyclase-C (GC-C) receptor agonist. Plecanatide activates GC-C receptors to stimulate cGMP synthesis with an EC50 of 190 nM in T84 cells assay. Plecanatide shows anti-inflammatory activity in models of murine colitis .
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Cat. No.: HY-N8245
CAS No.: 15718-49-7
Synonyms: Guanosine 2',3'-cyclic monophosphate sodium salt
Target:  

Drug Intermediate

Research Areas:  

Others

2',3'-cGMP sodium, a cGMP analogue, is an intermediate of RNA catalytic cleavage by binase .
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Cat. No.: HY-108741A
CAS No.: 1075732-84-1
Purity:  99.51%
Target:  

Guanylate Cyclase

Research Areas:  

Inflammation/Immunology Cancer

Plecanatide acetate, an analogue of Uroguanylin, is an orally active guanylate cyclase-C (GC-C) receptor agonist. Plecanatide acetate activates GC-C receptors to stimulate cGMP synthesis with an EC50 of 190 nM in T84 cells assay. Plecanatide acetate can be used for the research of chronic idiopathic constipation, and it also shows anti-inflammatory activity in models of murine colitis .
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Cat. No.: HY-N8245R
CAS No.: 15718-49-7
Synonyms: Guanosine 2',3'-cyclic monophosphate sodium salt (Standard)
Research Areas:  

Others

2',3'-cGMP sodium, a cGMP analogue, is an intermediate of RNA catalytic cleavage by binase .
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Cat. No.: HY-134311
CAS No.: 115993-88-9
Target:  

Fluorescent Dye

Research Areas:  

Others

8-NBD-cGMP is a fluorescent analog of cyclic guanosine monophosphate and a potent, membrane-permeable, fluorescent activator of cGMP-dependent protein kinase isozymes I α and I β. 8-NBD-cGMP is barely fluorescent in aqueous solution but fluoresces strongly in hydrophobic environments such as hydrophobic protein binding sites
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Cat. No.: HY-175080
Research Areas:  

Others

8-DY547-cGMP is a fluorescent cGMP analogue composed of a dye DY547 to position 8 of cGMP. 8-DY547-cGMP is a Cyclic nucleotide-gated A2 (CNGA2) ligand. 8-DY547-cGMP can activated CNGA2 channel. 8-DY547-cGMP can be used for simultaneously detection CNG channel activation and ligand binding .
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Cat. No.: HY-101379AR
CAS No.: 51116-01-9
8-Bromo-cGMP (sodium) (Standard) is the analytical standard of 8-Bromo-cGMP (sodium) (HY-101379A). This product is intended for research and analytical applications. 8-Bromo-cGMP sodium, a membrane-permeable analogue of cGMP, is a PKG (protein kinase G) activator. 8-Bromo-cGMP sodium significantly inhibits Ca2+ macroscopic currents and impairs insulin release stimulated with high K+ . 8-Bromo-cGMP sodium has antinociceptive effects and results in vasodilator responses .
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Cat. No.: HY-P11861
CNP analogue-1 is a long-acting, low-isoelectric point C-type natriuretic peptide (CNP) analog. CNP analogue-1 activates human natriuretic peptide receptor 2 (hNPR2) with an EC50 of 0.18 nM. CNP analogue-1 stimulates cGMP production and is resistant to neprilysin-mediated degradation. CNP analogue-1 induces baroreceptor-mediated heart rate elevation and enhances the maximal rates of cardiac contraction and relaxation. CNP analogue-1 can be used in the research of heart failure with preserved ejection fraction .
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Cat. No.: HY-180473
CAS No.: 57521-53-6
Research Areas:  

Others

6-Thio-cGMP is an analog of cyclic guanosine monophosphate (cGMP) .
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