2',3'-cGMP sodium
Based on 1 Customer Validation
2',3'-cGMP sodium, a cGMP analogue, is an intermediate of RNA catalytic cleavage by binase.
For research use only. We do not sell to patients.
- Purity: 99.28%
- CAS No.: 15718-49-7
- Formula: C10H11N5NaO7P
- Molecular Weight:367.19
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
2',3'-cGMP sodium (10 nM-100 μM, 120 min) reduces the active transport of [3H]3’,5’-cGMP into inside-out vesicles from human erythrocytes[2].
2',3'-cGMP sodium (2 μM) increases the ATPase activity[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 15718-49-7
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Appearance Solid
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Molecular Weight 367.19
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Formula C10H11N5NaO7P
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Color White to off-white
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SMILES
OC[C@H]1O[C@](N2C3=C(C(N=C(N3)N)=O)N=C2)([H])[C@@]4([H])[C@]1([H])OP(O4)(O[Na])=O
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Synonyms
Guanosine 2',3'-cyclic monophosphate sodium salt
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
H2O : 100 mg/mL (272.34 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Sokurenko JV, et al. [Identification of 2',3'-cGMP as an intermediate of RNA catalytic cleavage by binase and evaluation of its biological action]. Bioorg Khim. 2015 Jan-Feb;41(1):37-43. Russian. [Content Brief]
[2]. Boadu E, et al. Inhibition by guanosine cyclic monophosphate (cGMP) analogues of uptake of [(3)H]3',5'-cGMP without stimulation of ATPase activity in human erythrocyte inside-out vesicles. Biochem Pharmacol. 2001 Aug 15;62(4):425-9. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.7234 mL | 13.6169 mL | 27.2339 mL | 68.0846 mL |
| 5 mM | 0.5447 mL | 2.7234 mL | 5.4468 mL | 13.6169 mL | |
| 10 mM | 0.2723 mL | 1.3617 mL | 2.7234 mL | 6.8085 mL | |
| 15 mM | 0.1816 mL | 0.9078 mL | 1.8156 mL | 4.5390 mL | |
| 20 mM | 0.1362 mL | 0.6808 mL | 1.3617 mL | 3.4042 mL | |
| 25 mM | 0.1089 mL | 0.5447 mL | 1.0894 mL | 2.7234 mL | |
| 30 mM | 0.0908 mL | 0.4539 mL | 0.9078 mL | 2.2695 mL | |
| 40 mM | 0.0681 mL | 0.3404 mL | 0.6808 mL | 1.7021 mL | |
| 50 mM | 0.0545 mL | 0.2723 mL | 0.5447 mL | 1.3617 mL | |
| 60 mM | 0.0454 mL | 0.2269 mL | 0.4539 mL | 1.1347 mL | |
| 80 mM | 0.0340 mL | 0.1702 mL | 0.3404 mL | 0.8511 mL | |
| 100 mM | 0.0272 mL | 0.1362 mL | 0.2723 mL | 0.6808 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
2',3'-cGMP sodium Related Classifications
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