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coxsackievirus

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By Targets:	DNA/RNA Synthesis (1) Enterovirus (6) HCV (1) Monoamine Oxidase (2)
By Research Areas:	Endocrinology (1) Infection (6) Neurological Disease (1)

7

Inhibitors & Agonists

1

Natural
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5

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

cis-Resveratrol	Enterovirus	Infection
cis-Resveratrol exhibits signifcant antiviral activity. cis-Resveratrol inhibits enteroviruses with IC₅₀s of 12.2 µM and 37.6 µM for coxsackievirus B3 (CVB3) and enterovirus 71 (EV71), respectively .

DC07090 dihydrochloride	Enterovirus	Infection
DC07090 dihydrochloride is a low toxicity, potent, reversible and competitive non-peptidyl human enterovirus 71 3C protease inhibitor with an IC₅₀ and a K_i value for 21.72 μM and 23.29 μM. DC07090 dihydrochloride could also inhibit coxsackievirus A16 (CVA16) replication with an EC₅₀ value of 27.76 μM .

Pirlindole	Monoamine Oxidase Enterovirus	Infection Neurological Disease
Pirlindole is a selective and reversible MAO-A inhibitor . Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3) .

Golgicide A 3 Publications Verification GCA
Golgicide A (GCA) is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1 . Golgicide A drastically reduced replication of coxsackievirus B3 (CVB3) and other human enterovirus species .

Pirlindole mesylate	Monoamine Oxidase Enterovirus	Infection Endocrinology
Pirlindole mesylate is a selective and reversible MAO-A inhibitor. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3) .

(Rac)-Golgicide A (Rac)-GCA	Enterovirus	Infection
(Rac)-Golgicide A ((Rac)-GCA) is a racemate of Golgicide A. Golgicide A (GCA) is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1 .Golgicide A drastically reduced replication of coxsackievirus B3 (CVB3) and other human enterovirus species .

TTP-8307	Enterovirus DNA/RNA Synthesis HCV	Infection
TTP-8307 is a potent inhibitor of the replication of several rhino- and enteroviruses. TTP-8307 inhibits coxsackievirus B3 (CVB3; EC₅₀=1.2 μM) and poliovirus by interfering with the synthesis of viral RNA. TTP-8307 exerts antiviral activity through oxysterol-binding protein (OSBP) .

Species:	Virus (2) Human (1) Mouse (2)
Tag:	His (2) Avi (1) Fc (3)
Source:	HEK293 (3) Sf9 insect cells (2)

Cat. No.	Compare	Product Name	Species	Source

	CXADR Protein, Human (HEK293, His) rHucoxsackievirus and adenovirus receptor/CXADR, His ; coxsackievirus and Adenovirus Receptor; CAR; hCAR; CVB3-Binding Protein; coxsackievirus B-Adenovirus Receptor; HCVADR; CXADR; CAR	Human	HEK293
	CXADR proteins are components of the epithelial apical junction complex and, as cell adhesion molecules, are critical for the integrity of tight junctions. CXADR Protein, Human (HEK293, His) is the recombinant human-derived CXADR protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CXADR Protein, Human (HEK293, His) is 218 a.a., with molecular weight of ~32.0 kDa.

	CXADR Protein, Mouse (HEK293, Fc) rMucoxsackievirus and adenovirus receptor homolog/CXADR, Fc; coxsackievirus and adenovirus receptor homolog; CAR; Cxadr; CVB3 BP	Mouse	HEK293
	CXADR protein is a key component of the epithelial apical junction complex, which maintains the integrity of tight junctions and enables leukocyte migration through adhesive interactions with JAML. This interaction activates γ-δ T cells and promotes tissue repair through cell signaling involving PI3 kinase and MAP kinase. CXADR Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CXADR protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CXADR Protein, Mouse (HEK293, Fc) is 218 a.a., with molecular weight of 50-70 kDa.

	Coxsackievirus A16 VP1 Protein (295a.a, sf9, Fc) coxsackievirus A16 (Cox A16) (strain G-10) VP4 Protein; VP1 Protein; CV	Virus	Sf9 insect cells
	Coxsackievirus A16 (CVA16) can cause hand-foot-and-mouth disease (HFMD). CVA16 is a small, non-enveloped, icosahedral particle containing a single-stranded, positive-sense viral RNA genome of approximately 7.4 kb in length. CVA16 can be cleaved by viral proteases into 4 structural (VP1 to VP4) and 7 nonstructural (2A to 2C, and 3A to 3D) proteins. CVA16 interacts with its host receptors (cell surface heparan sulfate glycosaminoglycans and SCARB2 as its uncoating receptor) to enter into susceptible cells. Upon binding, CVA16 mature virions may transform to an uncoating intermediate state. Coxsackievirus A16 VP1 Protein is one of the capsid subunit protein of cleaved CVA16. Coxsackievirus A16 VP1 Protein (295a.a, sf9, Fc) is the recombinant Virus-derived Coxsackievirus A16 VP1 protein, expressed by Sf9 insect cells , with C-hFc labeled tag. The total length of Coxsackievirus A16 VP1 Protein (295a.a, sf9, Fc) is 295 a.a., with molecular weight of ~59.5 KDa.

	Coxsackievirus A16 VP4 Protein (68a.a, sf9, Fc) coxsackievirus A16 (Cox A16) (strain G-10) VP4 Protein; VP4 Protein; CV	Virus	Sf9 insect cells
	Coxsackievirus A16 (CVA16) can cause hand-foot-and-mouth disease (HFMD). CVA16 is a small, non-enveloped, icosahedral particle containing a single-stranded, positive-sense viral RNA genome of approximately 7.4 kb in length. CVA16 can be cleaved by viral proteases into 4 structural (VP1 to VP4) and 7 nonstructural (2A to 2C, and 3A to 3D) proteins. CVA16 interacts with its host receptors (cell surface heparan sulfate glycosaminoglycans and SCARB2 as its uncoating receptor) to enter into susceptible cells. Upon binding, CVA16 mature virions may transform to an uncoating intermediate state. Coxsackievirus A16 VP1 Protein is one of the capsid subunit protein of cleaved CVA16. Coxsackievirus A16 VP4 Protein (68a.a, sf9, Fc) is the recombinant Virus-derived Coxsackievirus A16 VP4 protein, expressed by Sf9 insect cells , with C-rFc labeled tag. The total length of Coxsackievirus A16 VP4 Protein (68a.a, sf9, Fc) is 68 a.a., with molecular weight of ~32.6 KDa.

	CXADR Protein, Mouse (Biotinylated, HEK293, Avi-His) coxsackievirus and adenovirus receptor homolog; CAR; Cxadr; CVB3 BP	Mouse	HEK293
	CXADR protein is a key component of the epithelial apical junction complex, which maintains the integrity of tight junctions and enables leukocyte migration through adhesive interactions with JAML. This interaction activates γ-δ T cells and promotes tissue repair through cell signaling involving PI3 kinase and MAP kinase. CXADR Protein, Mouse (Biotinylated, HEK293, Avi-His) is the recombinant mouse-derived CXADR protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of CXADR Protein, Mouse (Biotinylated, HEK293, Avi-His) is 218 a.a., with molecular weight of 30-40 kDa.

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