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Results for "

ets1

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Recombinant Proteins

8

Antibodies

4

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W002199

    6:2 FTOH; 1H,1H,2H,2H-Perfluoro-1-octanol; 2-(Perfluorohexyl)ethanol

    Bacterial Apoptosis ERK TNF Receptor Infection Neurological Disease
    6:2 Fluorotelomer alcohol (6:2 FTOH) is an orally active, blood-brain barrier-permeable modulator of cyclin D1 and ETS1. 6:2 Fluorotelomer alcohol downregulates cyclin D1 expression, upregulates ETS1 via the TNF-α/ERK 1/2 pathway, impairs mitochondrial membrane potential and respiratory function, increases reactive oxygen species levels, disrupts calcium homeostasis and activates endoplasmic reticulum stress markers, and induces cell proliferation inhibition and endothelial-mesenchymal transition. Furthermore, 6:2 Fluorotelomer alcohol induces morphological abnormalities in zebrafish embryos and liver developmental damage, while disrupting the brain immune microenvironment in mice, causing systemic toxicity and delayed pup maturation in CD-1 mice. 6:2 Fluorotelomer alcohol also induces cortical neuron apoptosis, glial cell activation, synaptic abnormalities, colonic barrier damage, intestinal dysbiosis and autism spectrum disorder-like symptoms in mice. 6:2 Fluorotelomer alcohol shows no mutagenic, clastogenic, primary skin/eye irritation or skin sensitizing effects, exhibits no selective reproductive toxicity in CD-1 mice, and is classified as GHS Category 4 for acute oral toxicity. 6:2 Fluorotelomer alcohol can be used in studies of neurodevelopmental disorders and autism spectrum disorders [1] .
    6:2 Fluorotelomer alcohol
  • HY-RS04562

    Small Interfering RNA (siRNA) Others

    ETS1 Human Pre-designed siRNA Set A contains three designed siRNAs for ETS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ETS1 Human Pre-designed siRNA Set A
    ETS1 Human Pre-designed siRNA Set A
  • HY-RS16879

    Small Interfering RNA (siRNA) Others

    Ets1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ets1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Ets1 Mouse Pre-designed siRNA Set A
    Ets1 Mouse Pre-designed siRNA Set A
  • HY-RS23321

    Small Interfering RNA (siRNA) Others

    Ets1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ets1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Ets1 Rat Pre-designed siRNA Set A
    Ets1 Rat Pre-designed siRNA Set A
  • HY-RS28129

    Small Interfering RNA (siRNA) Others
    Kcnh8 Rat Pre-designed siRNA Set A contains three designed siRNAs for Kcnh8 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Kcnh8 Rat Pre-designed siRNA Set A
    Kcnh8 Rat Pre-designed siRNA Set A

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