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Isoforms Recommended: CA
Results for "

hCA VA

" in MedChemExpress (MCE) Product Catalog:
Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-175441
    Carbonic anhydrase activator 1

    		Carbonic Anhydrase Cardiovascular Disease Neurological Disease Cancer
    Carbonic anhydrase activator 1 (Compound 17) is an orally active and a BBB-penetrable Carbonic anhydrase (CA) activator with KAs of 7.8, 3.9  and 2.1 μM for hCA I, hCA VA and hCA VII. Carbonic anhydrase activator 1 can be used for cancers, glaucoma, cardiovascular diseases and neurodegenerative disorders like epilepsy research .
    Carbonic anhydrase activator 1
  • HY-151578
    DPP IV/hCA II-IN-1

    		Dipeptidyl Peptidase Carbonic Anhydrase Metabolic Disease
    DPP IV/hCA II-IN-1 is a potent and selective dipeptidyl peptidase IV (DPP IV) and carbonic anhydrase (CA) inhibitor with an IC50 value of 0.049 μM for DPP IV and with Ki values of 0.0361, 0.0428, 0.0941, 0.1328, 0.2615, and 3.034 μM for CA II, CA VB, CA VA, CA IX, CA I, and CA IV, respectively .
    DPP IV/hCA II-IN-1
  • HY-181684
    PDE5/CA-IN-1

    		Phosphodiesterase (PDE) Carbonic Anhydrase Neurological Disease
    PDE5/CA-IN-1 is a dual PDE5 and carbonic anhydrase (CA) inhibitor, with IC50 values of 0.41, 38.4, and 9.1 nM against PDE5, hCA II, and hCA VA, respectively. PDE5/CA-IN-1 inhibits multiple hCA subtypes associated with Alzheimer's disease. As a cytoprotective agent and oxidative stress alleviator, PDE5/CA-IN-1 reduces oxidative stress, and prevents recognition memory and working memory impairments. PDE5/CA-IN-1 is available for the research of Alzheimer's disease .
    PDE5/CA-IN-1
  • HY-182070
    Carbonic anhydrase-IN-38

    		Carbonic Anhydrase Cancer
    Carbonic anhydrase-IN-38 (compound 5c) is a carbonic anhydrase inhibitor with antiproliferative activity, with Ki values of 576.2 nM, 41.3 nM and 86.9 nM against hCA VII, hCA IX and hCA XII, respectively. Carbonic anhydrase-IN-38 can be used in research related to triple-negative breast cancer and glioblastoma .
    Carbonic anhydrase-IN-38
  • HY-180189
    Carbonic anhydrase-IN-37

    		Carbonic Anhydrase Neurological Disease
    Carbonic anhydrase-IN-37 (compound 9a) is a potent and orally active carbonic anhydrase (CA) inhibitor with Kis of 9.7 and 1.0 nM for hCA VA and hCA VB, respectively. Carbonic anhydrase-IN-37 shows anti allodynic and antihyperalgesic effects on Paclitaxel (HY-B0015)-induced neuropathic pain in mice. Carbonic anhydrase-IN-37 can be used for neuropathic pain research .
    Carbonic anhydrase-IN-37

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