Carbonic anhydrase-IN-37
Carbonic anhydrase-IN-37 (compound 9a) is a potent and orally active carbonic anhydrase (CA) inhibitor with Kis of 9.7 and 1.0 nM for hCA VA and hCA VB, respectively. Carbonic anhydrase-IN-37 shows anti allodynic and antihyperalgesic effects on Paclitaxel (HY-B0015)-induced neuropathic pain in mice. Carbonic anhydrase-IN-37 can be used for neuropathic pain research.
For research use only. We do not sell to patients.
- Formula: C17H20N4O5S2
- Molecular Weight:424.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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hCA VA 9.7 nM (Ki) |
hCA VB 1.0 nM (Ki) |
hCA I 50.0 nM (Ki) |
hCA II 73.0 nM (Ki) |
hCA VII 43.8 nM (Ki) |
hCA IX 15.0 nM (Ki) |
hCA XII 24.4 nM (Ki) |
Chemical Information
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Molecular Weight 424.49
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Formula C17H20N4O5S2
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SMILES
O=S(C1=CC=CC=C1)(NC(N2CCN(CC2)C3=CC=C(C=C3)S(N)(=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Carbonic anhydrase-IN-37 Related Classifications
HY-180189 Related Classifications
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