Carbonic anhydrase activator 1
Carbonic anhydrase activator 1 (Compound 17) is an orally active and a BBB-penetrable Carbonic anhydrase (CA) activator with KAs of 7.8, 3.9 and 2.1 μM for hCA I, hCA VA and hCA VII. Carbonic anhydrase activator 1 can be used for cancers, glaucoma, cardiovascular diseases and neurodegenerative disorders like epilepsy research.
For research use only. We do not sell to patients.
- CAS No.: 2374923-30-3
- Formula: C17H11N5OS
- Molecular Weight:333.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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hCA I 7.8 μM (KA) |
hCA II >150 μM (KA) |
hCA VII 2.1 μM (KA) |
hCA VA 3.9 μM (KA) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | EC50 |
>1000 nM
Compound: 15
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Agonist activity at human A2B expressed in CHO cells assessed as stimulation of cAMP production by alphascreen assay
Agonist activity at human A2B expressed in CHO cells assessed as stimulation of cAMP production by alphascreen assay
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[PMID: 31306001] |
Chemical Information
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CAS No. 2374923-30-3
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Molecular Weight 333.37
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Formula C17H11N5OS
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SMILES
N#CC1=C(C2=CC=CO2)C(C#N)=C(N)N=C1SCC3=CC=NC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Carbonic anhydrase activator 1 Related Classifications
HY-175441 Related Classifications
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