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Results for "

methionine biosynthesis

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (2) Androgen Receptor (4) Apoptosis (2) Aryl Hydrocarbon Receptor (4) Bacterial (1) Biochemical Assay Reagents (2) Cytochrome P450 (4) Drug Intermediate (1) Endogenous Metabolite (1) Environmental Pollutants (2) Fungal (10) HIV (2) iGluR (1) Isotope-Labeled Compounds (4) Ornithine decarboxylase (ODC) (1) PERK (4) Reference Standards (4)
By Research Areas:	Cancer (3) Endocrinology (4) Infection (13)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: MetAP Methionine Adenosyltransferase (MAT)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-106634

Mitoguazone 5 Publications Verification Methylglyoxal-bis(guanylhydrazone); MGBG; Methyl-GAG	HIV Apoptosis	Infection Cancer
Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitive *S-adenosyl-methionine* decarboxylase (SAMDC)** inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkin's and non-Hodgkin's lymphoma treatment .

HY-B2033

Pyrimethanil 1 Publications Verification	Environmental Pollutants Fungal	Infection
Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops . Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection .

HY-116214

Cyprodinil CGA-219417	Environmental Pollutants Aryl Hydrocarbon Receptor Androgen Receptor Fungal PERK Cytochrome P450	Infection Endocrinology
Cyprodinil (CGA-219417) is a broad-spectrum anilinopyrimidine fungicide and an activator of the aryl hydrocarbon receptor. Cyprodinil also has anti-androgenic and androgenic activities. Cyprodinil can inhibit the biosynthesis of methionine in plant-pathogenic fungi and protect fruits and vegetables from a variety of pathogens .

HY-119543

O-Succinyl-L-homoserine	Amino Acid Derivatives	Others
O-Succinyl-L-homoserine is a homoserine derivative. O-Succinyl-L-homoserine is an intermediate in the biosynthesis of methionine in Escherichia coli and Salmonella typhimurium .

HY-B2033R

Pyrimethanil (Standard) 1 Publications Verification	Reference Standards Fungal	Infection
Pyrimethanil (Standard) is the analytical standard of Pyrimethanil. This product is intended for research and analytical applications. Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops . Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection .

HY-B2033S

Pyrimethanil-13C,15N2	Isotope-Labeled Compounds Fungal	Infection
Pyrimethanil- ¹³C, ¹⁵N₂ is the ¹³C-labeled and ¹⁵N-labeled Pyrimethanil. Pyrimethanil is an?anilinopyrimidine?and broad-spectrum?contact fungicide for the control of Botrytis spp. on a wide variety of crops . Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in?Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection .

HY-W585967

O-Acetyl-L-homoserine hydrochloride	Drug Intermediate	Others
O-Acetyl-L-Homoserine hydrochloride (OAH hydrochloride) is an intermediate of L-Methionine (HY-N0326) biosynthesis. O-Acetyl-L-Homoserine hydrochloride is an OAH sulfhydrylase (CaMet15p) inhibitor

HY-E70079

Cystathionine β-lyase, Recombinant Microorganisms CBL	Biochemical Assay Reagents	Infection
Cystathionine β-lyase, Recombinant Microorganisms (CBL) is an enzyme that catalyzes the breakdown of cystathionine to homocysteine, the penultimate step in methionine biosynthesis. Cystathionine β-lyase is important for bacterial virulence .

HY-116214R

Cyprodinil (Standard) CGA-219417 (Standard)	Reference Standards Fungal Androgen Receptor Aryl Hydrocarbon Receptor PERK Cytochrome P450	Infection Endocrinology
Cyprodinil (Standard) (CGA-219417 (Standard)) is the analytical standard of Cyprodinil (HY-116214). This product is intended for research and analytical applications. Cyprodinil (CGA-219417) is a broad-spectrum anilinopyrimidine fungicide and an activator of the aryl hydrocarbon receptor. Cyprodinil also has anti-androgenic and androgenic activities. Cyprodinil can inhibit the biosynthesis of methionine in plant-pathogenic fungi and protect fruits and vegetables from a variety of pathogens.

HY-106634R

Mitoguazone (Standard) Methylglyoxal-bis(guanylhydrazone) (Standard); MGBG (Standard); Methyl-GAG (Standard)	Reference Standards HIV Apoptosis	Infection Cancer
Mitoguazone (Standard) is the analytical standard of Mitoguazone. This product is intended for research and analytical applications. Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitive *S-adenosyl-methionine* decarboxylase (SAMDC)** inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkin's and non-Hodgkin's lymphoma treatment .

HY-125430

Padanamide A	Amino Acid Derivatives	Others
Padanamide A is a linear tetrapeptide without proteinogenic amino acids. Padanamide A has the activity of inhibiting the biosynthesis of cysteine and methionine .

HY-N15023

Azoxybacilin	Fungal	Infection
Azoxybacilin can inhibit the sulfur fixation reaction in methionine biosynthesis and has strong anti-filamentous fungal activity .

HY-117089R

Tetraconazole (Standard)	Reference Standards Fungal	Infection
Tetraconazole (Standard) is the analytical standard of Tetraconazole. This product is intended for research and analytical applications. Tetraconazole, a chiral triazole fungicide, is widely used for the prevention of plant disease in wheat fields . Tetraconazole alters the methionine and ergosterol biosynthesis pathways in Saccharomyces yeasts promoting changes on volatile derived compounds .

HY-W127737

Methylcobalamin hydrate Mecobalamin hydrate	Biochemical Assay Reagents	Others
Methylcobalamin Hydrate is a coenzyme required for methionine biosynthesis. Vitamins (hematopoiesis). It acts as a histamine receptor, Alzheimer study. Methylcobalamin is also used in the research of peripheral neuropathy, diabetic neuropathy, and as an initial research for amyotrophic lateral sclerosis. It can be used to prevent or research pathologies caused by vitamin B12 deficiency, such as pernicious anemia.

HY-B2033S1

Pyrimethanil-d5	Fungal Isotope-Labeled Compounds	Others
Pyrimethanil-d₅ is the deuterium labeled Pyrimethanil (HY-B2033). Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops . Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection .

HY-116214S

Cyprodinil-d5 CGA-219417-d₅	Isotope-Labeled Compounds Fungal Androgen Receptor Aryl Hydrocarbon Receptor PERK Cytochrome P450	Infection Endocrinology
Cyprodinil-d₅(CGA-219417-d₅) is the deuterium labeled Cyprodinil (HY-116214). Cyprodinil (CGA-219417) is a broad-spectrum anilinopyrimidine fungicide and an activator of the aryl hydrocarbon receptor. Cyprodinil also has anti-androgenic and androgenic activities. Cyprodinil can inhibit the biosynthesis of methionine in plant-pathogenic fungi and protect fruits and vegetables from a variety of pathogens .

HY-116214S1

Cyprodinil-13C6 CGA-219417-¹³C₆	Isotope-Labeled Compounds Fungal Androgen Receptor Aryl Hydrocarbon Receptor PERK Cytochrome P450	Infection Endocrinology
Cyprodinil- ¹³C₆ (CGA-219417- ¹³C₆) is the ¹³C₆ labeled Cyprodinil (HY-116214). Cyprodinil (CGA-219417) is a broad-spectrum anilinopyrimidine fungicide and an activator of the aryl hydrocarbon receptor. Cyprodinil also has anti-androgenic and androgenic activities. Cyprodinil can inhibit the biosynthesis of methionine in plant-pathogenic fungi and protect fruits and vegetables from a variety of pathogens .

HY-180999

Antibacterial agent 317	Bacterial	Infection
Antibacterial agent 317 (Compound 5h) is an antibacterial agent. Antibacterial agent 317 has multiple antibacterial mechanisms, including enhancing cell membrane permeability, inhibiting EPS production and cell membrane formation, and also interfering with flagella and methionine biosynthesis. Antibacterial agent 317 significantly suppresses the growth of tested plant pathogens, namely, Xanthomonas oryzae pv oryzicola (Xoc) and Xanthomonas oryzae pv oryzae (Xoo) with EC₅₀ values of 1.53 and 6.07 μg/mL, respectively .

HY-23964

4-Methylthio-2-oxobutanoic acid MTOB	Ornithine decarboxylase (ODC)	Cancer
4-Methylthio-2-oxobutanoic acid (MTOB) is an ornithine decarboxylase inhibitor. 4-Methylthio-2-oxobutanoic acid reduces ornithine decarboxylase protein levels and enzymatic activity. 4-Methylthio-2-oxobutanoic acid is formed in cells in the Met salvage pathway from methylthioadenosine. 4-Methylthio-2-oxobutanoic acid inhibits cancer cells growth. 4-Methylthio-2-oxobutanoic acid can be used for the research of cancer .

HY-W051199

O-Phosphono-L-homoserine o-Phosphohomoserine	Endogenous Metabolite iGluR	Others
O-Phosphono-L-homoserine (o-Phosphohomoserine) is an intermediate in threonine synthesis in bacteria and plants, and can also be hijacked by MetM in some Streptomyces species to enter a novel methionine synthesis pathway. O-Phosphono-L-homoserine acts as a weak antagonist of the NMDA receptor. O-Phosphono-L-homoserine can be used as a substrate for studies on amino acid metabolism of the aspartate family, a control for mechanism studies of PLP enzymes, and a reference for structure-activity relationship studies of NMDA receptor ligands .

Cat. No.	Product Name	Type

HY-W127737

Methylcobalamin hydrate Mecobalamin hydrate	Biochemical Assay Reagents
Methylcobalamin Hydrate is a coenzyme required for methionine biosynthesis. Vitamins (hematopoiesis). It acts as a histamine receptor, Alzheimer study. Methylcobalamin is also used in the research of peripheral neuropathy, diabetic neuropathy, and as an initial research for amyotrophic lateral sclerosis. It can be used to prevent or research pathologies caused by vitamin B12 deficiency, such as pernicious anemia.

Methylcobalamin hydrate

Mecobalamin hydrate

Biochemical Assay Reagents

Methylcobalamin Hydrate is a coenzyme required for methionine biosynthesis. Vitamins (hematopoiesis). It acts as a histamine receptor, Alzheimer study. Methylcobalamin is also used in the research of peripheral neuropathy, diabetic neuropathy, and as an initial research for amyotrophic lateral sclerosis. It can be used to prevent or research pathologies caused by vitamin B12 deficiency, such as pernicious anemia.

Cat. No.	Product Name	Target	Research Area

HY-119543

O-Succinyl-L-homoserine	Amino Acid Derivatives	Others
O-Succinyl-L-homoserine is a homoserine derivative. O-Succinyl-L-homoserine is an intermediate in the biosynthesis of methionine in Escherichia coli and Salmonella typhimurium .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-119543

O-Succinyl-L-homoserine	Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Amino Acid Derivatives
O-Succinyl-L-homoserine is a homoserine derivative. O-Succinyl-L-homoserine is an intermediate in the biosynthesis of methionine in Escherichia coli and Salmonella typhimurium .

HY-N15023

Azoxybacilin	Natural Products Microorganisms Source Classification	Fungal
Azoxybacilin can inhibit the sulfur fixation reaction in methionine biosynthesis and has strong anti-filamentous fungal activity .

HY-23964

4-Methylthio-2-oxobutanoic acid MTOB	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Ornithine decarboxylase (ODC)
4-Methylthio-2-oxobutanoic acid (MTOB) is an ornithine decarboxylase inhibitor. 4-Methylthio-2-oxobutanoic acid reduces ornithine decarboxylase protein levels and enzymatic activity. 4-Methylthio-2-oxobutanoic acid is formed in cells in the Met salvage pathway from methylthioadenosine. 4-Methylthio-2-oxobutanoic acid inhibits cancer cells growth. 4-Methylthio-2-oxobutanoic acid can be used for the research of cancer .

HY-W051199

O-Phosphono-L-homoserine o-Phosphohomoserine	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Endogenous Metabolite iGluR
O-Phosphono-L-homoserine (o-Phosphohomoserine) is an intermediate in threonine synthesis in bacteria and plants, and can also be hijacked by MetM in some Streptomyces species to enter a novel methionine synthesis pathway. O-Phosphono-L-homoserine acts as a weak antagonist of the NMDA receptor. O-Phosphono-L-homoserine can be used as a substrate for studies on amino acid metabolism of the aspartate family, a control for mechanism studies of PLP enzymes, and a reference for structure-activity relationship studies of NMDA receptor ligands .

Cat. No.	Product Name	Chemical Structure

HY-B2033S

Pyrimethanil-13C,15N2
Pyrimethanil- ¹³C, ¹⁵N₂ is the ¹³C-labeled and ¹⁵N-labeled Pyrimethanil. Pyrimethanil is an?anilinopyrimidine?and broad-spectrum?contact fungicide for the control of Botrytis spp. on a wide variety of crops . Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in?Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection .

Pyrimethanil-13C,15N2

Pyrimethanil- ¹³C, ¹⁵N₂ is the ¹³C-labeled and ¹⁵N-labeled Pyrimethanil. Pyrimethanil is an?anilinopyrimidine?and broad-spectrum?contact fungicide for the control of Botrytis spp. on a wide variety of crops . Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in?Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection .

HY-B2033S1

Pyrimethanil-d5
Pyrimethanil-d₅ is the deuterium labeled Pyrimethanil (HY-B2033). Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops . Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection .

Pyrimethanil-d5

Pyrimethanil-d₅ is the deuterium labeled Pyrimethanil (HY-B2033). Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops . Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection .

HY-116214S

Cyprodinil-d5
Cyprodinil-d₅(CGA-219417-d₅) is the deuterium labeled Cyprodinil (HY-116214). Cyprodinil (CGA-219417) is a broad-spectrum anilinopyrimidine fungicide and an activator of the aryl hydrocarbon receptor. Cyprodinil also has anti-androgenic and androgenic activities. Cyprodinil can inhibit the biosynthesis of methionine in plant-pathogenic fungi and protect fruits and vegetables from a variety of pathogens .

Cyprodinil-d5

Cyprodinil-d₅(CGA-219417-d₅) is the deuterium labeled Cyprodinil (HY-116214). Cyprodinil (CGA-219417) is a broad-spectrum anilinopyrimidine fungicide and an activator of the aryl hydrocarbon receptor. Cyprodinil also has anti-androgenic and androgenic activities. Cyprodinil can inhibit the biosynthesis of methionine in plant-pathogenic fungi and protect fruits and vegetables from a variety of pathogens .

HY-116214S1

Cyprodinil-13C6
Cyprodinil- ¹³C₆ (CGA-219417- ¹³C₆) is the ¹³C₆ labeled Cyprodinil (HY-116214). Cyprodinil (CGA-219417) is a broad-spectrum anilinopyrimidine fungicide and an activator of the aryl hydrocarbon receptor. Cyprodinil also has anti-androgenic and androgenic activities. Cyprodinil can inhibit the biosynthesis of methionine in plant-pathogenic fungi and protect fruits and vegetables from a variety of pathogens .

Cyprodinil-13C6

Cyprodinil- ¹³C₆ (CGA-219417- ¹³C₆) is the ¹³C₆ labeled Cyprodinil (HY-116214). Cyprodinil (CGA-219417) is a broad-spectrum anilinopyrimidine fungicide and an activator of the aryl hydrocarbon receptor. Cyprodinil also has anti-androgenic and androgenic activities. Cyprodinil can inhibit the biosynthesis of methionine in plant-pathogenic fungi and protect fruits and vegetables from a variety of pathogens .

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methionine biosynthesis

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

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Products