mutase

By Targets:	Bacterial (2) Calcium Channel (1) Endogenous Metabolite (4) iGluR (1) Phosphatase (5)
By Research Areas:	Cancer (5) Infection (2) Metabolic Disease (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-118391

Benzoyl-L-phenylalanine N-Benzoyl-L-phenylalanine; Bz-L-Phe-OH	Others	Others
Benzoyl-L-phenylalanine (N-Benzoyl-L-phenylalanine) is a *chorisate mutase-prephenate dehydrogenase* inhibitor .

HY-101143

PGMI-004A

Phosphatase Cancer

PGMI-004A is a potent phosphoglycerate mutase 1 (PGAM1) inhibitor with an IC₅₀ of 13.1 μM.
HY-128681

PGAM1-IN-1

1 Publications Verification

Phosphatase Cancer

PGAM1-IN-1 is a phosphoglycerate mutase 1 (PGAM1) inhibitor with an IC₅₀ of 6.4 μM .
HY-128682

PGAM1-IN-2

Phosphatase Cancer

PGAM1-IN-2 is a phosphoglycerate mutase 1 (PGAM1) inhibitor with an IC₅₀ of 2.1 μM .

PGMI-004A	Phosphatase	Cancer
PGMI-004A is a potent *phosphoglycerate mutase* 1 (PGAM1) inhibitor with an IC₅₀** of 13.1 μM.

PGAM1-IN-1 1 Publications Verification	Phosphatase	Cancer
PGAM1-IN-1 is a *phosphoglycerate mutase* 1 (PGAM1) inhibitor with an IC₅₀** of 6.4 μM .

PGAM1-IN-2	Phosphatase	Cancer
PGAM1-IN-2 is a *phosphoglycerate mutase* 1 (PGAM1) inhibitor with an IC₅₀** of 2.1 μM .

HY-112790

Adenosylcobalamin Coenzyme B12; Cobamamide; AdoCbl	Endogenous Metabolite	Metabolic Disease
Adenosylcobalamin (Coenzyme B12;Cobamamide;AdoCbl) is an active form of Vitamin B₁₂ which is a cofactor for methylmalonyl CoA mutase

HY-146652

UGM-IN-3	Bacterial	Infection
UGM-IN-3 (compound 10a) is a *UDP-galactopyranose mutase* (UGM) inhibitor with a K_d of 66 μM. UGM-IN-3 inhibits the growth of Mycobacterium tuberculosis** with a MIC value of 6.2 μg/mL .

HY-126791

Methylmalonyl-CoA Isosuccinyl coenzyme A; Methylmalonyl coenzyme A	Endogenous Metabolite	Others
Methylmalonyl coenzyme A (Methylmalonyl-CoA) is a catabolite of valine, isoleucine, methionine, threonine, odd-chain fatty acids, and cholesterol. Methylmalonyl coenzyme A tetralithium is converted to succinyl-CoA by enzymatic reaction of methylmalonyl-CoA mutase (MCM) with coenzyme vitamin B12 .

HY-126791A

Methylmalonyl-CoA tetralithium Isosuccinyl coenzyme A tetralithium; Methylmalonyl coenzyme tetralithium	Endogenous Metabolite	Others
Methylmalonyl-CoA (Methylmalonyl coenzyme A) tetralithium is a catabolite of valine, isoleucine, methionine, threonine, odd-chain fatty acids, and cholesterol. Methylmalonyl-CoA tetralithium is converted to succinyl-CoA by enzymatic reaction of methylmalonyl-CoA mutase (MCM) with coenzyme vitamin B12 .

HY-151514

Antituberculosis agent-5	Bacterial	Infection
Antituberculosis agent-5 (compound 52) is a nitrofuranylamide derivative, inhibits M. tuberculosis UDP-Gal mutase. Antituberculosis agent-5 inhibits Glf activity with an IC₅₀ value of 99 μM/mL and resists tuberculosis (TB) with a MIC value of 1.6 μg/mL .

HY-138877A

Phosphoglycolic acid lithium	Phosphatase	Cancer
Phosphoglycolic acid (lithium) is a competitive inhibitor of phosphoglycerate mutase (PGAM)-B, an enzyme of the glycolytic pathway. Phosphoglycolic acid increases basal and fMLF-induced levels of G6P in intact neutrophils. Phosphoglycolic acid thereby increases upstream intermediates in neutrophils, thereby amplifying the respiratory oxidative burst .

HY-148510

HKB99	Phosphatase	Cancer
HKB99 is an allosteric inhibitor of phosphoglycerate mutase 1 (PGAM1). HKB99 inhibits the formation of invasive pseudopodia and increases the level of PAI-2 in vitro. HKB99 increases the oxidative stress, activates JNK/c-Jun and suppresses AKT and ERK. HKB99 can be used for the research of non-small-cell lung cancer (NSCLC) .

HY-N0215

L-Phenylalanine Phenylalanine	Calcium Channel iGluR Endogenous Metabolite	Metabolic Disease
L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca ⁺ channels antagonist with a K_i of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (K_B of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals .

HY-124890

Thr101	Others	Metabolic Disease
Thr101 is an inhibitor (IC₅₀=2.9 μM) of phosphomannose isomerase (PMI).PMI can compete with phosphomannose mutase 2 (PMM2) for the binding site of Man-6-P and convert mannose-6-phosphate (Man-6-P) into fructose-6-phosphate (Fru-6-P) .Thr101 only specifically inhibits PMI and not PMM2. Thr101 can be used for research of congenital disorder of glycosylation type Ia (CDG-Ia) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-112790

Adenosylcobalamin Coenzyme B12; Cobamamide; AdoCbl	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Adenosylcobalamin (Coenzyme B12;Cobamamide;AdoCbl) is an active form of Vitamin B₁₂ which is a cofactor for methylmalonyl CoA mutase

HY-N0215

L-Phenylalanine Phenylalanine	Structural Classification Microorganisms Classification of Application Fields Animals Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Calcium Channel iGluR Endogenous Metabolite
L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca ⁺ channels antagonist with a K_i of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (K_B of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals .

HY-126791

Methylmalonyl-CoA Isosuccinyl coenzyme A; Methylmalonyl coenzyme A	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Methylmalonyl coenzyme A (Methylmalonyl-CoA) is a catabolite of valine, isoleucine, methionine, threonine, odd-chain fatty acids, and cholesterol. Methylmalonyl coenzyme A tetralithium is converted to succinyl-CoA by enzymatic reaction of methylmalonyl-CoA mutase (MCM) with coenzyme vitamin B12 .

HY-126791A

Methylmalonyl-CoA tetralithium Isosuccinyl coenzyme A tetralithium; Methylmalonyl coenzyme tetralithium	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Methylmalonyl-CoA (Methylmalonyl coenzyme A) tetralithium is a catabolite of valine, isoleucine, methionine, threonine, odd-chain fatty acids, and cholesterol. Methylmalonyl-CoA tetralithium is converted to succinyl-CoA by enzymatic reaction of methylmalonyl-CoA mutase (MCM) with coenzyme vitamin B12 .

Species:	Human (3)
Tag:	His (2) Tag Free (1) Strep (1)
Source:	E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P701962

	PGAM1 Protein, Human PGAM1; Phosphoglycerate mutase 1; BPG-dependent PGAM 1; Phosphoglycerate mutase isozyme B; PGAM-B	Human	E. coli
	PGAM1 protein plays a pivotal role in glycolysis by catalyzing the vital interconversion of 2-phosphoglycerate and 3-phosphoglycerate. Additionally, it is instrumental in the conversion of (2R)-2,3-bisphosphoglycerate to (2R)-3-phospho-glyceroyl phosphate, further contributing to the intricate metabolic processes associated with glycolytic pathways. PGAM1 Protein, Human is the recombinant human-derived PGAM1 protein, expressed by E. coli , with tag free. The total length of PGAM1 Protein, Human is 254 a.a., .

HY-P701963

	PGAM1 Protein, Human (His, Strep) PGAM1; Phosphoglycerate mutase 1; BPG-dependent PGAM 1; Phosphoglycerate mutase isozyme B; PGAM-B	Human	E. coli
	PGAM1 protein plays a pivotal role in glycolysis by catalyzing the vital interconversion of 2-phosphoglycerate and 3-phosphoglycerate. Additionally, it is instrumental in the conversion of (2R)-2,3-bisphosphoglycerate to (2R)-3-phospho-glyceroyl phosphate, further contributing to the intricate metabolic processes associated with glycolytic pathways. PGAM1 Protein, Human (His, Strep) is the recombinant human-derived PGAM1 protein, expressed by E. coli , with N-Strep, N-6*His labeled tag. The total length of PGAM1 Protein, Human (His, Strep) is 254 a.a., .

HY-P7665

	BPGM Protein, Human (His) rHuBPGM, His; BPGM; Bisphosphoglycerate mutase;	Human	E. coli
	BPGM Protein, Human (His) expresses in E. coliwith a His tag. Bisphosphoglycerate mutase is an erythrocyte-specific enzyme catalyzing a series of intermolecular phosphoryl group transfer reactions. Its main function is to synthesize 2,3-bisphosphoglycerate, the allosteric effector of hemoglobin.


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Cat. No.	Product Name	Application	Reactivity

HY-P80222

*Methylmalonyl Coenzyme A mutase* Antibody**	WB, IHC-P	Human, Mouse, Rat
Methylmalonyl Coenzyme A mutase Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 83 kDa, targeting to Methylmalonyl Coenzyme A mutase. It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse, Rat.

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