Benzoyl-L-phenylalanine
Based on 1 Customer Validation
Benzoyl-L-phenylalanine (N-Benzoyl-L-phenylalanine) is a chorisate mutase-prephenate dehydrogenase inhibitor.
For research use only. We do not sell to patients.
- Purity: 99.68%
- CAS No.: 2566-22-5
- Formula: C16H15NO3
- Molecular Weight:269.30
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Metabolism/Protease Compound Library
HY-L012
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Protease Inhibitor Library
HY-L147
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MCE Bioactive Compound Library
HY-L001V
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Amino Acid Metabolism Compound Library
HY-L189
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Non-natural Amino Acid Compound Library
HY-L198
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High-Throughput Bioactive Compound Library
HY-L205
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MCE Kinase Hinge Binder Fragment Library
HY-L907
Biological Activity
Chorisate Mutase-prephenate Dehydrogenase[1]
Chemical Information
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CAS No. 2566-22-5
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Appearance Solid
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Molecular Weight 269.30
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Formula C16H15NO3
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Color White to off-white
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SMILES
O=C([C@@H](NC(C1=CC=CC=C1)=O)CC2=CC=CC=C2)O
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Synonyms
N-Benzoyl-L-phenylalanine; Bz-L-Phe-OH
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (371.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (9.28 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (9.28 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (273 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 3.7133 mL | 18.5667 mL | 37.1333 mL | 92.8333 mL |
| 5 mM | 0.7427 mL | 3.7133 mL | 7.4267 mL | 18.5667 mL | |
| 10 mM | 0.3713 mL | 1.8567 mL | 3.7133 mL | 9.2833 mL | |
| 15 mM | 0.2476 mL | 1.2378 mL | 2.4756 mL | 6.1889 mL | |
| 20 mM | 0.1857 mL | 0.9283 mL | 1.8567 mL | 4.6417 mL | |
| 25 mM | 0.1485 mL | 0.7427 mL | 1.4853 mL | 3.7133 mL | |
| 30 mM | 0.1238 mL | 0.6189 mL | 1.2378 mL | 3.0944 mL | |
| 40 mM | 0.0928 mL | 0.4642 mL | 0.9283 mL | 2.3208 mL | |
| 50 mM | 0.0743 mL | 0.3713 mL | 0.7427 mL | 1.8567 mL | |
| 60 mM | 0.0619 mL | 0.3094 mL | 0.6189 mL | 1.5472 mL | |
| 80 mM | 0.0464 mL | 0.2321 mL | 0.4642 mL | 1.1604 mL | |
| 100 mM | 0.0371 mL | 0.1857 mL | 0.3713 mL | 0.9283 mL |
Benzoyl-L-phenylalanine Related Classifications
HY-118391 Related Classifications
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