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Results for "

myelocytic

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15187
    Filanesib
    5+ Cited Publications

    ARRY-520

    		 Kinesin Apoptosis Cancer
    Filanesib (ARRY-520) is a selective and noncompetitive kinesin spindle protein (KSP) inhibitor, with an IC50 of 6 nM for human KSP. Filanesib induces cell death by apoptosis in vitro. Filanesib has potent anti-proliferative activity .
    Filanesib
  • HY-N0117
    Indirubin
    10+ Cited Publications

    Couroupitine B; Indigo red; Indigopurpurin

    		 Apoptosis Cancer
    Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia .
    Indirubin
  • HY-N0117A
    (Z)-Indirubin

    (Z)-Couroupitine B; (Z)-Indigo red; (Z)-Indigopurpurin

    		 Apoptosis Cancer
    (Z)-Indirubin is an isomer of Indirubin (HY-N0117). Indirubin is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia .
    (Z)-Indirubin
  • HY-177023
    Ap5dT

    		Nucleoside Antimetabolite/Analog Cancer
    Ap5dT is a cytosolic thymidine kinase and mitochondrial enzyme inhibitor with Kis of 0.12 μM and 0.50 μM, respectively. Ap5dT can be used for the study of acute myelocytic leukemia .
    Ap5dT
  • HY-N0117R
    Indirubin (Standard)

    Couroupitine B (Standard); Indigo red (Standard); Indigopurpurin (Standard)

    		 Reference Standards Apoptosis Cancer
    Indirubin (Standard) is the analytical standard of Indirubin. This product is intended for research and analytical applications. Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia .
    Indirubin (Standard)
  • HY-15187C
    Filanesib hydrochloride
    5+ Cited Publications

    ARRY-520 hydrochloride

    		 Kinesin Apoptosis Neurological Disease Cancer
    Filanesib (ARRY-520) hydrochloride is a selective and noncompetitive kinesin spindle protein (KSP) inhibitor, with an IC50 of 6 nM for human KSP. Filanesib induces cell death by apoptosis in vitro. Filanesib has potent anti-proliferative activity .
    Filanesib hydrochloride
  • HY-15187B
    Filanesib TFA

    ARRY-520 TFA

    		 Kinesin Cancer
    Filanesib TFA (ARRY-520 TFA) is a selective kinesin spindle protein (KSP) inhibitor, with an IC50 of 6 nM for human KSP. Filanesib TFA induces cell death by apoptosis in vitro. Filanesib TFA has potent anti-proliferative activity .
    Filanesib TFA
  • HY-W739369
    Cyanocobalamin-e-methylamide

    		Drug Derivative Cancer
    Cyanocobalamin-e-methylamide is a Vitamin B12 (HY-B0315) analogue. Cyanocobalamin-e-methylamide exerts a plasma blocking effect on 57Co-cyanocobalamin. Cyanocobalamin-e-methylamide can be used for the research of chronic myelocytic leukaemia .
    Cyanocobalamin-e-methylamide
  • HY-181800
    SHP2-IN-47

    		SHP2 Akt ERK Apoptosis Cancer
    SHP2-IN-47 is a selective and potent SHP2 inhibitor with an IC50 of 0.80 μM. SHP2-IN-47 exhibits potent inhibitory activity against SHP2 E76K (IC50 = 0.37 μM). SHP2-IN-47 functionally inhibits protein tyrosine phosphatase domains and downregulates SHP2-mediated phosphorylation of AKT and ERK. SHP2-IN-47 induces apoptosis and suppresses proliferation of cancer cells. SHP2-IN-47 can be used for the research of cancer, such as acute myelocytic leukemia .
    SHP2-IN-47

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