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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
neonatal myocytes
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "neonatal myocytes" in MCE Product Catalog:
2
Target:
Research Areas:
Reverse T3 is a thyroid hormone that can be generated by deiodination of the prohormone thyroxine . Reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes .
Cat. No.: HY-W010696R
CAS No.: 5817-39-0
Synonyms: 3′,5′,3-Triiodothyronine (Standard)
Research Areas:
Reverse T3 (Standard) is the analytical standard of Reverse T3. This product is intended for research and analytical applications. Reverse T3 is a thyroid hormone that can be generated by deiodination of the prohormone thyroxine . Reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes .
Cat. No.: HY-A0113
CAS No.: 90139-06-3
Synonyms: Ro 31-3113
Research Areas:
Cilazaprilat is an inhibitor of angiotensin-converting enzyme (ACE; IC50=0.7 nM for the rat enzyme) and an active metabolite of Cilazapril (HY-A0043). It decreases creatine kinase release in primary neonatal rat cardiac myocytes in an in vitro model of ischemia-reperfusion injury induced by hypoxia and reoxygenation when used at a concentration of 10 μM.3 Intra-arterial administration of cilazaprilat (3 μg/kg per minute) increases coronary blood flow and fractional shortening in a dog model of coronary hypoperfusion-induced myocardial ischemia.
Cat. No.: HY-12773A
CAS No.: 86383-32-6
Synonyms: GPV-129 hydrochloride
Target:
Research Areas:
5-Hydroxy Propafenone (hydrochloride) is an inhibitor of cardiac myocyte repolarizing currents. 5-Hydroxy Propafenone is an active metabolite of propafenone. 5-Hydroxy Propafenone (hydrochloride) inhibits transient outward potassium current (Ito) in isolated human arterial myocytes with an IC50 of 1.5 μM. 5-Hydroxy Propafenone (hydrochloride) is potent Ito inhibitor in neonatal rat ventricular myocytes .
Cat. No.: HY-106761
CAS No.: 90729-41-2
Target:
Research Areas:
Oxodipine, a dihydropyridine-type calcium antagonist, inhibits KCl-induced aortic contraction in rabbits and reduces cardiac force in less potent rat ventricular test-paper contractions. In rat cultured neonatal ventricular myocytes, Oxodipine reduces L-type Ca currents (I) with an IC50 of 0.24 μM, and against T-type Ca currents (I) with an IC50 of 0.41 μM. Oxodipine causes constipation in mice and gingival hyperplasia in dogs .
Research Areas:
Succinylcholine iodide (Suxamethonium iodide) is a depolarizing neuromuscular blocker with rapid onset and short duration of action. Succinylcholine iodide also acts as an agonist of the Acetylcholine receptor. Succinylcholine iodide is used for emergency airway management .
Cat. No.: HY-164295A
CAS No.: 133681-84-2
Research Areas:
U-78517 dihydrochloride, a Trolox (HY-101445) analog, is a potent antioxidant. U-78517 dihydrochloride inhibits DCVC (HY-19717)-induced lipid peroxidation, scavenges DPPH, oxygen- and nitrogen-based free radicals. U-78517 dihydrochloride attenuates hypoxic injury in iaolated cardiac myocytes. U-78517 dihydrochloride can be used for the research of hypoxic injury, cerebral ischemia, and cardiovascular disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
