5-Hydroxy Propafenone hydrochloride
5-Hydroxy Propafenone (hydrochloride) is an inhibitor of cardiac myocyte repolarizing currents. 5-Hydroxy Propafenone is an active metabolite of propafenone. 5-Hydroxy Propafenone (hydrochloride) inhibits transient outward potassium current (Ito) in isolated human arterial myocytes with an IC50 of 1.5 μM. 5-Hydroxy Propafenone (hydrochloride) is potent Ito inhibitor in neonatal rat ventricular myocytes.
For research use only. We do not sell to patients.
- CAS No.: 86383-32-6
- Formula: C21H28ClNO4
- Molecular Weight:393.90
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 86383-32-6
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Molecular Weight 393.90
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Formula C21H28ClNO4
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SMILES
[H]Cl.O=C(C1=CC(O)=CC=C1OCC(O)CNCCC)CCC2=CC=CC=C2
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Synonyms
GPV-129 hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
5-Hydroxy Propafenone hydrochloride Related Classifications
HY-12773A Related Classifications
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