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Cat. No.: HY-12773A

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5-Hydroxy Propafenone hydrochloride

(Synonyms: GPV-129 hydrochloride)

5-Hydroxy Propafenone (hydrochloride) is an inhibitor of cardiac myocyte repolarizing currents. 5-Hydroxy Propafenone is an active metabolite of propafenone. 5-Hydroxy Propafenone (hydrochloride) inhibits transient outward potassium current (Ito) in isolated human arterial myocytes with an IC₅₀ of 1.5 μM. 5-Hydroxy Propafenone (hydrochloride) is potent Ito inhibitor in neonatal rat ventricular myocytes.

For research use only. We do not sell to patients.

CAS No.: 86383-32-6
Formula: C₂₁H₂₈ClNO₄
Molecular Weight:393.90

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

5-Hydroxy Propafenone hydrochloride Chemical Structure

CAS No.: 86383-32-6

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Fluorescent Dye

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Biological Activity

Description

Chemical Information

CAS No. 86383-32-6
Molecular Weight 393.90
Formula C₂₁H₂₈ClNO₄
SMILES

[H]Cl.O=C(C1=CC(O)=CC=C1OCC(O)CNCCC)CCC2=CC=CC=C2
Synonyms

GPV-129 hydrochloride
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Cahill, S. A., et al., (2001). Transient outward current inhibition by propafenone and 5-hydroxypropafenone in cultured neonatal rat ventricular myocytes. Journal of cardiovascular pharmacology, 38(3), 460–467. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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5-Hydroxy Propafenone hydrochloride

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5-Hydroxy Propafenone hydrochloride

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

5-Hydroxy Propafenone hydrochloride Related Classifications

HY-12773A Related Classifications