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omega-6

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By Targets:	Apoptosis (1) Biochemical Assay Reagents (2) Endogenous Metabolite (9) Free Fatty Acid Receptor (2) Reactive Oxygen Species (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (5) Inflammation/Immunology (5) Metabolic Disease (6) Neurological Disease (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W071746

Linolelaidic acid Linoelaidic acid	Endogenous Metabolite	Cardiovascular Disease
Linolelaidic acid (Linoelaidic acid), an omega-6 trans fatty acid, acts as a source of energy. Linolelaidic acid is an essential nutrient, adding in enteral, parenteral, and infant formulas. Linolelaidic acid can be used for heart diseases research .

HY-109590

Arachidonic acid Maximum Cited Publications 16 Publications Verification Immunocytophyt	Endogenous Metabolite	Inflammation/Immunology
Arachidonic acid (Immunocytophyt) is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonic acid also acts as the substrate for various lipid mediators, such as prostaglandins (PGs). Arachidonic acid improves cognitive response and cardiovascular function .

HY-N7140

Gamma-Linolenic acid 2 Publications Verification γ-Linolenic acid	Endogenous Metabolite	Metabolic Disease
Gamma-linolenic acid (γ-Linolenic acid) is an omega-6 (n-6), 18 carbon (18C-) polyunsaturated fatty acid (PUFA) extracted from Perilla frutescens. Gamma-linolenic acid supplements could restore needed PUFAs and mitigate the disease .

HY-109590A

Arachidonic acid sodium salt Immunocytophyt sodium salt	Endogenous Metabolite	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Arachidonic acid (Immunocytophyt) sodium salt is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonic acid sodium salt also acts as the substrate for various lipid mediators, such as prostaglandins (PGs). Arachidonic acid sodium salt improves cognitive response and cardiovascular function .

HY-N7140R

Gamma-Linolenic acid (Standard) γ-Linolenic acid (Standard)	Endogenous Metabolite	Metabolic Disease
Gamma-Linolenic acid (Standard) is the analytical standard of Gamma-Linolenic acid. This product is intended for research and analytical applications. Gamma-linolenic acid (γ-Linolenic acid) is an omega-6 (n-6), 18 carbon (18C-) polyunsaturated fatty acid (PUFA) extracted from Perilla frutescens. Gamma-linolenic acid supplements could restore needed PUFAs and mitigate the disease .

HY-N7864

all-cis-4,7,10,13,16-Docosapentaenoic acid all-cis-4,7,10,13,16-Docosapentaenoic acid; Osbond acid	Biochemical Assay Reagents	Others
Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.

HY-145504

12-Dipalmitoyl-3-Linoelaidoyl-rac-glycerol 1,2-Palmitin-3-Linoelaidin	Biochemical Assay Reagents	Metabolic Disease
12-Dipalmitoyl-3-Linoelaidoyl-rac-glycerol is a triacylglycerol containing palmitic acid (HY-N0830) at the sn-1 and sn-2 positions and linoelaidic acid (HY-W071746) at the sn-3 position. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells. Linolelaidic acid, an omega-6 trans fatty acid, acts as a source of energy. Linolelaidic acid is an essential nutrient, adding in enteral, parenteral, and infant formulas. Linolelaidic acid can be used for heart diseases research .

HY-W718405

(5Z,14Z)-5,14-Eicosadienoic acid

Others Others

(5Z,14Z)-5,14-Eicosadienoic acid is a ω-6 C20:2 fatty acid .

(5Z,14Z)-5,14-Eicosadienoic acid	Others	Others
(5Z,14Z)-5,14-Eicosadienoic acid is a ω-6 C20:2 fatty acid .

HY-116722

(2E)-4-Hydroperoxy-2-nonenal	Reactive Oxygen Species	Inflammation/Immunology
(2E)-4-Hydroperoxy-2-nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids, and can be used as a marker of oxidative stress .

HY-A0143

Dihomo-γ-linolenic acid 2 Publications Verification DGLA; all-cis-8,11,14-Eicosatrienoic acid
Dihomo-γ-linolenic acid (DGLA) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system .

HY-W009276

γ-Linolenic Acid methyl ester Methyl GLA	Apoptosis	Cancer
γ-Linolenic Acid methyl ester (Methyl GLA) is an esterified version of γ-Linolenic Acid (GLA), which is an ω-6 fatty acid, serves as melanoma cell proliferation inhibitors. γ-Linolenic Acid methyl ester inhibits ADP-induced blood platelet aggregation and induces apoptosis .

HY-A0143A

Dihomo-γ-linolenic acid sodium DGLA sodium; all-cis-8,11,14-Eicosatrienoic acid sodium	Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology Cancer
Dihomo-γ-linolenic acid (DGLA; all-cis-8,11,14-Eicosatrienoic acid) sodium is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid (sodium) attenuates atherosclerosis in the apolipoprotein E deficient mouse model system .

HY-114610

13Z,16Z-Docosadienoic acid	Endogenous Metabolite Free Fatty Acid Receptor	Metabolic Disease
13Z,16Z-Docosadienoic acid, a ω-6 polyunsaturated fatty acid, possesses anti-borreliae effect. 13Z,16Z-Docosadienoic acid, as a long-chain fatty acid (LCFA), is a free fatty acid receptor 4 (FFAR4 or GPR120, a LCFA receptor) agonist .

HY-A0143S

Dihomo-γ-linolenic acid-d6 DGLA-d₆; all-cis-8,11,14-Eicosatrienoic acid-d₆	Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology Cancer
Dihomo-γ-linolenic acid-d₆ (DGLA-d₆) is the deuterium labeled Dihomo-γ-linolenic acid. Dihomo-γ-linolenic acid (all-cis-8,11,14-Eicosatrienoic acid) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system[1][2][3].

HY-19996

AH-7614	Free Fatty Acid Receptor	Metabolic Disease
AH-7614 is a potent and selective FFA4 (GPR120) antagonist, with pIC₅₀s of 7.1, 8.1, and 8.1 for human, mouse, and rat FFA4, respectively. AH-7614 has selectivity for FFA4 over FFA1 (pIC₅₀<4.6). AH-7614 is able to block effects of both the polyunsaturated ω-6 fatty acid linoleic acid and the synthetic FFA4 agonist .

HY-N0729

Linoleic acid 5+ Cited Publications	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease Cancer
Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

all-cis-4,7,10,13,16-Docosapentaenoic acid all-cis-4,7,10,13,16-Docosapentaenoic acid; Osbond acid	Biochemical Assay Reagents
Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W071746

Linolelaidic acid Linoelaidic acid	Cardiovascular Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Linolelaidic acid (Linoelaidic acid), an omega-6 trans fatty acid, acts as a source of energy. Linolelaidic acid is an essential nutrient, adding in enteral, parenteral, and infant formulas. Linolelaidic acid can be used for heart diseases research .

HY-109590

Arachidonic acid Maximum Cited Publications 16 Publications Verification Immunocytophyt	Structural Classification Human Gut Microbiota Metabolites Microorganisms Animals Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
Arachidonic acid (Immunocytophyt) is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonic acid also acts as the substrate for various lipid mediators, such as prostaglandins (PGs). Arachidonic acid improves cognitive response and cardiovascular function .

HY-N7140

Gamma-Linolenic acid 2 Publications Verification γ-Linolenic acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Labiatae Source classification Disease markers Metabolic Disease Espeletia schultzii Wedd. Endocrine diseases Plants Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Gamma-linolenic acid (γ-Linolenic acid) is an omega-6 (n-6), 18 carbon (18C-) polyunsaturated fatty acid (PUFA) extracted from Perilla frutescens. Gamma-linolenic acid supplements could restore needed PUFAs and mitigate the disease .

HY-N7140R

Gamma-Linolenic acid (Standard) γ-Linolenic acid (Standard)	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Labiatae Source classification Disease markers Metabolic Disease Espeletia schultzii Wedd. Endocrine diseases Plants Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Gamma-Linolenic acid (Standard) is the analytical standard of Gamma-Linolenic acid. This product is intended for research and analytical applications. Gamma-linolenic acid (γ-Linolenic acid) is an omega-6 (n-6), 18 carbon (18C-) polyunsaturated fatty acid (PUFA) extracted from Perilla frutescens. Gamma-linolenic acid supplements could restore needed PUFAs and mitigate the disease .

HY-A0143A

Dihomo-γ-linolenic acid sodium DGLA sodium; all-cis-8,11,14-Eicosatrienoic acid sodium	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Endogenous Metabolite
Dihomo-γ-linolenic acid (DGLA; all-cis-8,11,14-Eicosatrienoic acid) sodium is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid (sodium) attenuates atherosclerosis in the apolipoprotein E deficient mouse model system .

HY-114610

13Z,16Z-Docosadienoic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Free Fatty Acid Receptor
13Z,16Z-Docosadienoic acid, a ω-6 polyunsaturated fatty acid, possesses anti-borreliae effect. 13Z,16Z-Docosadienoic acid, as a long-chain fatty acid (LCFA), is a free fatty acid receptor 4 (FFAR4 or GPR120, a LCFA receptor) agonist .

HY-N0729

Linoleic acid 5+ Cited Publications	Cardiovascular Disease Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Endogenous metabolite Disease Research Fields Biological Pesticide Research Agricultural Research	Endogenous Metabolite
Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

Cat. No.	Product Name	Chemical Structure

HY-A0143S

Dihomo-γ-linolenic acid-d6
Dihomo-γ-linolenic acid-d₆ (DGLA-d₆) is the deuterium labeled Dihomo-γ-linolenic acid. Dihomo-γ-linolenic acid (all-cis-8,11,14-Eicosatrienoic acid) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system[1][2][3].

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omega-6

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Natural
Products