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  3. 13Z,16Z-Docosadienoic acid

13Z,16Z-Docosadienoic acid is a GPR120 agonist with bactericidal activity. 13Z,16Z-Docosadienoic acid serves as a potential biomarker for canine mammary tumors. 13Z,16Z-Docosadienoic acid is used in the research of bacterial infections, Lyme disease, Graves' disease and mammary tumors.

For research use only. We do not sell to patients.

13Z,16Z-Docosadienoic acid

13Z,16Z-Docosadienoic acid Chemical Structure

CAS No. : 17735-98-7

Size Price Stock Quantity
Solvent
1 mg (29.71 mM * 100 μL in Ethanol) In-stock
Solvent
5 mg (29.71 mM * 500 μL in Ethanol) In-stock

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Other Forms of 13Z,16Z-Docosadienoic acid:

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Description

13Z,16Z-Docosadienoic acid is a GPR120 agonist with bactericidal activity. 13Z,16Z-Docosadienoic acid serves as a potential biomarker for canine mammary tumors. 13Z,16Z-Docosadienoic acid is used in the research of bacterial infections, Lyme disease, Graves' disease and mammary tumors[1][2][3][4][5].

IC50 & Target

Human Endogenous Metabolite

 

Cellular Effect
Cell Line Type Value Description References
RBL-2H3 IC50
> 50 μM
Compound: 8
Antiallergic activity in rat RBL2H3 cells assessed as inhibition of DNP-HSA-mediated degranulation by measuring decrease in beta-hexosaminidase activity preincubated for 30 mins followed by DNP-HSA stimulation and measured after 30 mins by 4-nitrophenyl 2-acetamido-2-deoxy-beta-D-glucopyranoside substrate based assay
Antiallergic activity in rat RBL2H3 cells assessed as inhibition of DNP-HSA-mediated degranulation by measuring decrease in beta-hexosaminidase activity preincubated for 30 mins followed by DNP-HSA stimulation and measured after 30 mins by 4-nitrophenyl 2-acetamido-2-deoxy-beta-D-glucopyranoside substrate based assay
[PMID: 31618024]
In Vitro

13Z,16Z-Docosadienoic acid (24-72 h) exhibits bacteriostatic activity against log-phase and stationary-phase Borrelia burgdorferi s.s. (strain B31) and Borrelia garinii (strain CIP103362), with an MIC of 0.025 mg/mL; it also shows bactericidal activity, with an MBC90 of 0.5 mg/mL[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

13Z,16Z-Docosadienoic acid is significantly upregulated in canine mammary tumor tissues and serves as a candidate biomarker for the disease[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

336.55

Formula

C22H40O2

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

CCCCC/C=C\C/C=C\CCCCCCCCCCCC(O)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Solution, -20°C, protect from light, 2 years

Purity & Documentation

Purity: 99.0%

References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
13Z,16Z-Docosadienoic acid
Cat. No.:
HY-114610
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