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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
photoswitchable
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "photoswitchable" in MCE Product Catalog:
Cat. No.: HY-W106234
CAS No.: 1562-93-2
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4-(Phenyldiazenyl)benzoic acid is a photosensitive and photoswitchable TRPA1 agonist that can be used as pharmacological tools for study of pain signaling.
Cat. No.: HY-161092A
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KIO-301 chloride hydrochloride is an azobenzene photoswitchable compound that blocks voltage-gated ion channels, including hyperpolarization-activated cyclic nucleotide gating (HCN, during exposure to visible light) ) and voltage-gated potassium channels (voltage-gated potassium channels) .
Cat. No.: HY-110358
Purity: 98.68%
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QAQ dichloride, a photoswitchable voltage-gated Nav and Kv channels blocker, blocks channels in its trans form (of the azobenzene photoswitch), but not in its cis form. QAQ dichloride is membrane-impermeant and only infiltrates pain-sensing neurons that express endogenous import channels. QAQ dichloride acts as a light-sensitive analgesic and can be used for studying of signaling mechanisms in acute and chronic pain .
Cat. No.: HY-N15794
CAS No.: 2389048-52-4
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Cat. No.: HY-160209
CAS No.: 1643463-61-9
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KIO-301 is a photoswitchable HCN channel blocker, and can be used as the vitreous “light switch” molecule that reactivates retinitis pigmentosa .
Cat. No.: HY-N15799
CAS No.: 2260670-59-3
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Cat. No.: HY-N15782
CAS No.: 1985595-31-0
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Cat. No.: HY-110209
CAS No.: 1459809-09-6
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AC4 is a trans antagonist upon voltageactivation of TRPV1 and as cis antagonist of TRPV1 currents upon stimulation with Capsaicin (HY-10448). AC4 demonstrates that a photoswitchable antagonist and an agonist can be used in concert .
Cat. No.: HY-126748
CAS No.: 2223023-78-5
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VUF14862 is a stable and fatigue-resistant photoswitchable GPCR antagonist targeting the histamine H3 receptor (H3R) pathway. VUF14862 binds to H3R with >10-fold increased affinity upon 360 nm irradiation. VUF14862 can be used for spatiotemporal studies of H3R signaling .
Cat. No.: HY-139904
CAS No.: 71291-80-0
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TRPA1 Antagonist 3 is a photoswitchable TRPA1 agonist that enables optical control of the TRPA1 channel.
Cat. No.: HY-N15783
CAS No.: 2456348-60-8
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Cat. No.: HY-126424
CAS No.: 2230617-93-1
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OptoDArG is a photoswitchable probe that has the activity to recognize lipid-gated pores by controlling TRPC3 channels and can be used as a tool to study the lipid sensing mechanism of TRPC channels.
Cat. No.: HY-N15781
CAS No.: 1882060-21-0
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Cat. No.: HY-125667
CAS No.: 1620951-72-5
Synonyms: Photoamiloride-1
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PA1 is a photoswitchable epithelial sodium channel (ENaC) blocker. PA1 can switch to cis-PA1 at 400nm and trans-PA1 at 500nm. PA1 inhibits δ/αENaC, αβγENaC, and δβγENaC, with IC50 values of 4.3nM, 90 nM, and 390 nM, respectively .
Cat. No.: HY-110358A
CAS No.: 1204416-85-2
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QAQ dichloride dichloride, a photoswitchable voltage-gated Nav and Kv channels blocker, blocks channels in its trans form (of the azobenzene photoswitch), but not in its cis form. QAQ dichloride dichloride is membrane-impermeant and only infiltrates pain-sensing neurons that express endogenous import channels. QAQ dichloride dichloride acts as a light-sensitive analgesic and can be used for studying of signaling mechanisms in acute and chronic pain .
Cat. No.: HY-N16250
CAS No.: 2260670-56-0
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Azo SM is a photoswitchable lipid.
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Cintriamide (Cintramide) (Compound 5) is a key intermediate for the synthesis of photoswitchable epothilone-based microtubule stabiliser .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
