NAMPT activator-6
NAMPT activator-6 is a nicotinamide phosphoribosyltransferase (NAMPT) activator. NAMPT activator-6 can be used for the synthesis of PROTACs, such as PROTAC NAMPT Degrader-1 (HY-163440). NAMPT activator-6 applies to the research of ovarian cancer.
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- No. CAS: 2237267-86-4
- Fòrmula: C17H21N5O3S
- Peso molecular:375.45
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
In Vitro
NAMPT activator-6 serves as the target protein ligand for PROTAC NAMPT Degrader-1 (HY-163440), a potent PROTAC targeting NAMPT with a DC50 value of 217 nM[1].
NAMPT activator-6 (example 210) has NAMPT activator activity[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2237267-86-4
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Peso molecular 375.45
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Fòrmula C17H21N5O3S
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SMILES
O=C(NCC1=CC=NC=C1)NC2=CC=C(S(=O)(N3CCNCC3)=O)C=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)