PROTAC NAMPT Degrader-1
PROTAC NAMPT Degrader-1 is a potent PROTAC targeting NAMPT with aDC50 value of 217 nM. PROTAC NAMPT Degrader-1 has anti-proliferative activity with an IC50 value of 0.12μM against A2780 cells. (Structure Note: PINK, NAMPT activator (HY-163445); Blue, VHL ligand (HY-163440); Black, linker).
For research use only. We do not sell to patients.
- CAS No.: 3102963-15-2
- Formula: C57H69N13O8S2
- Molecular Weight:1128.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Biological Activity
Chemical Information
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CAS No. 3102963-15-2
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Molecular Weight 1128.37
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Formula C57H69N13O8S2
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SMILES
O=C(NCC1=CC=NC=C1)NC2=CC=C(C=C2)S(=O)(N3CCN(CC3)C(C4=CC=C(C=C4)/N=N/C5=C(N(N=C5C)CCCCC(N[C@@H](C(C)(C)C)C(N6[C@@H](C[C@H](C6)O)C(N[C@H](C7=CC=C(C=C7)C8=C(N=CS8)C)C)=O)=O)=O)C)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC NAMPT Degrader-1 Related Classifications
HY-163440 Related Classifications
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