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Pathways Recommended: Membrane Transporter/Ion Channel
Results for "

surface membrane receptor

" in MedChemExpress (MCE) Product Catalog:

13

Inhibitors & Agonists

1

Screening Libraries

9

Biochemical Assay Reagents

1

Peptides

3

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-148118A

    LYTACs Cancer
    Tri-GalNAc(OAc)3 TFA is a trivalent N-acetylgalactosamine (GalNAc) derivative that can be used to synthesize GalNAc-LYTAC. Tri-GalNAc is a specific ligand targeting the asialoglycoprotein receptor (ASGPR), mediating the endocytosis and transport of cell surface proteins (such as EGFR, HER2) to lysosomes for degradation by lysosomal targeting chimeras (LYTACs). Tri-GalNAc significantly reduces the level of target proteins and inhibits downstream signaling pathways (such as EGFR-mediated Akt and MAPK signals). Tri-GalNAc(OAc)3 TFA can be used for hepatocyte targeting studies, and can degrade carcinogenic membrane proteins and inhibit tumor cell proliferation in liver cancer cell models .
    Tri-GalNAc(OAc)3 TFA
  • HY-B0633D

    CD44 Endogenous Metabolite Bacterial Akt PI3K Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Hyaluronic acid sodium (MW 200-1560) is a biopolymer composed of repeating disaccharide units, with a molecular weight of 200-1560. Hyaluronic acid sodium is a major component of the extracellular matrix (ECM). It is synthesized on the plasma membrane. Hyaluronic acid sodium exerts its effects by binding to receptors CD44 and RHAMM. Hyaluronic acid sodium activates PI3K-Akt signaling. Hyaluronic acid sodium also enhances cell invasion and angiogenesis by promoting or stimulating the binding of proteolytic MMP-9 to the cell surface. Elevated hyaluronic acid levels are associated with tumor cell growth, adhesion, migration, invasion, and angiogenesis in digestive system cancers. Hyaluronic acid sodium is involved in tissue remodeling and rapid cell proliferation in several physiological processes, including embryonic morphogenesis and wound healing. Hyaluronic acid sodium can be used as a regulator of cancer-associated lymphangiogenesis. Hyaluronic acid sodium can be used as a drug delivery carrier for sodium butyrate, enhancing its anti-proliferative activity against breast cancer cell lines. Hyaluronic acid sodium can lubricate the corneal endothelium. Hyaluronic acid sodium can improve tissue hydration and enhance the resistance of cells to mechanical damage. Hyaluronic acid sodium has been conjugated with antibodies to ensure that the active compound continues to exert its effects at the site of inflammation. Hyaluronic acid sodium can be used in research in the fields of osteoarthritis, ophthalmology, cosmetic dermatology, oncology, and liver diseases .
    Hyaluronic acid sodium (MW 200-1560)
  • HY-B0633E

    Hyaluronan, low endotoxin; Hyaluronate, low endotoxin

    Endogenous Metabolite CD44 Bacterial Akt PI3K Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Hyaluronic acid, low endotoxin (Hyaluronan, low endotoxin) is a biopolymer composed of repeating disaccharide units containing low levels of endotoxin. Hyaluronic acid is a major component of the extracellular matrix (ECM). It is synthesized on the plasma membrane. Hyaluronic acid exerts its effects by binding to receptors CD44 and RHAMM. Hyaluronic acid activates PI3K-Akt signaling. Hyaluronic acid also enhances cell invasion and angiogenesis by promoting or stimulating the binding of proteolytic MMP-9 to the cell surface. Elevated hyaluronic acid levels are associated with tumor cell growth, adhesion, migration, invasion, and angiogenesis in digestive system cancers. Hyaluronic acid is involved in tissue remodeling and rapid cell proliferation in several physiological processes, including embryonic morphogenesis and wound healing. Hyaluronic acid can be used as a regulator of cancer-associated lymphangiogenesis. Hyaluronic acid can be used as a drug delivery carrier for sodium butyrate, enhancing its anti-proliferative activity against breast cancer cell lines. Hyaluronic acid can lubricate the corneal endothelium. Hyaluronic acid can improve tissue hydration and enhance the resistance of cells to mechanical damage. Hyaluronic acid has been conjugated with antibodies to ensure that the active compound continues to exert its effects at the site of inflammation. Hyaluronic acid can be used in research in the fields of osteoarthritis, ophthalmology, cosmetic dermatology, oncology, and liver diseases .
    Hyaluronic acid, low endotoxin
  • HY-NP143

    Reactive Oxygen Species (ROS) Adrenergic Receptor Inflammation/Immunology
    Nerve Growth Factor 2.5S,murine submaxillary gland is a neurotrophic polypeptide and protein growth factor isolated from murine submaxillary glands. Nerve Growth Factor 2.5S,murine submaxillary gland increases the survival rate, phagocytic capacity and superoxide anion production level of mouse cells. Nerve Growth Factor 2.5S,murine submaxillary gland acts through cell membrane surface receptors to mediate the differentiation and maintenance of adrenergic neurons in the sympathetic nervous system. Nerve Growth Factor 2.5S,murine submaxillary gland loses its activity and undergoes dimer dissociation due to oxidation; it remains active after modification of specific tryptophan residues, while its tyrosine residues are not essential for activity. Nerve Growth Factor 2.5S,murine submaxillary gland may play a role in the inflammatory process .
    Nerve Growth Factor 2.5S,murine submaxillary gland
  • HY-P2969

    Endogenous Metabolite Metabolic Disease
    Complement factor I is a serine protease that downregulates complement activity in the fluid phase and/or on cell surfaces in conjunction with one of its cofactors, factor H (FH), complement receptor 1 (CR1/CD35), C4 binding protein (C4BP) or membrane cofactor protein (MCP/CD46) .
    Complement factor I
  • HY-P5487

    iGluR Others
    GluR23Y is a biological active peptide. (This GluR23Y peptide was used in ELISA cell-surface assay for the insulin-stimulated endocytosis of native AMPA receptors in cultured hippocampal neurons. GluR23Y prevented any insulin-induced reduction. The blockade of insulin action was observed when the GluR23Y peptide was delivered into neurons by fusing it to the membrane transduction domain of HIV-1.)
    GluR23Y
  • HY-174960

    6-Arm-PEG400-Folate

    Biochemical Assay Reagents Others
    6-Arm-PEG400-FA (6-Arm-PEG400-Folate) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
    6-Arm-PEG400-FA
  • HY-174960A

    6-Arm-PEG600-Folate

    Biochemical Assay Reagents Others
    6-Arm-PEG600-FA (6-Arm-PEG600-Folate) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
    6-Arm-PEG600-FA
  • HY-174960B

    6-Arm-PEG1000-Folate

    Biochemical Assay Reagents Others
    6-Arm-PEG1000-FA (6-Arm-PEG1000-Folate) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
    6-Arm-PEG1000-FA
  • HY-174960C

    6-Arm-PEG2000-Folate

    Biochemical Assay Reagents Others
    6-Arm-PEG2000-FA (6-Arm-PEG2000-Folate) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
    6-Arm-PEG2000-FA
  • HY-174960D

    6-Arm-PEG3400-Folate

    Biochemical Assay Reagents Others
    6-Arm-PEG3400-FA (6-Arm-PEG3400-Folate) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
    6-Arm-PEG3400-FA
  • HY-174960E

    6-Arm-PEG5000-Folate

    Biochemical Assay Reagents Others
    6-Arm-PEG5000-FA (6-Arm-PEG5000-Folate) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
    6-Arm-PEG5000-FA
  • HY-174960H

    6-Arm-PEG10000-Folate

    Biochemical Assay Reagents Others
    6-Arm-PEG10000-FA (6-Arm-PEG10000-Folate) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
    6-Arm-PEG10000-FA

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