2. Others NF-κB Apoptosis
  3. Biochemical Assay Reagents NF-κB Environmental Pollutants Apoptosis
  4. Sodium benzoate

Sodium benzoate is an orally active pharmaceutical excipient, such as an antibacterial agent, preservative, lubricant, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs.Sodium benzoate activates NF-κB and induces Apoptosis. Sodium benzoate induces immune suppression and produces reproductively toxic. Sodium benzoate can be used for colon cancer and immune disease research.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Sodium benzoate

Sodium benzoate 화학구조

CAS No. : 532-32-1

사이즈 가격 재고 수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in DMSO 해외재고보유
Solid
100 mg 해외재고보유
500 mg 해외재고보유
1 g 해외재고보유
5 g 해외재고보유
10 g 해외재고보유
25 g 해외재고보유
50 g 해외재고보유
100 g 해외재고보유
> 100 g   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 2 publication(s) in Google Scholar

Other Forms of Sodium benzoate:

Sodium benzoate Related Antibodies

Top Publications Citing Use of Products

View All NF-κB Isoform Specific Products:

View All Isoforms
NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

Sodium benzoate is an orally active pharmaceutical excipient, such as an antibacterial agent, preservative, lubricant, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs.Sodium benzoate activates NF-κB and induces Apoptosis. Sodium benzoate induces immune suppression and produces reproductively toxic. Sodium benzoate can be used for colon cancer and immune disease research[1][2][3][4][5].

In Vitro

Sodium benzoate (0.125-3 mg/mL, 48 h) does not completely protect the PC12 cells to aluminum-induced free radicals toxicity[4].
Sodium benzoate (0-2500 mg/mL, 72 h) affects the functional and activation status of splenocytes at non cytotoxic dose, with inducing immune suppression[5].
Sodium benzoate (0.39-200 mM, 24 h) activates NF-κB and induces apoptosis in HCT116 cells[6].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Sodium benzoate Related Antibodies
In Vivo

Sodium benzoate (125-500 ppm, diet, 8 weeks) affects body weight, food intake, lipid profile and biochemical indices of kidney and liver function in mice[2].
Sodium benzoate (0-1000 mg/kg, p.o., 90 consecutive days) is dose-dependently reproductively toxic to male rats, with reducing sperm parameters, alters plasma levels of sex hormones[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
분자량

144.10

화학식

C7H5NaO2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O[Na])C1=CC=CC=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
용액&용해도
In Vitro: 

H2O : ≥ 100 mg/mL (693.96 mM)

DMSO : 5 mg/mL (34.70 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.9396 mL 34.6981 mL 69.3962 mL
5 mM 1.3879 mL 6.9396 mL 13.8792 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
순도&문서

Purity: 99.87%

SDS (396 KB)

COA (249 KB) HNMR (128 KB) RP-HPLC (255 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 6.9396 mL 34.6981 mL 69.3962 mL 173.4906 mL
5 mM 1.3879 mL 6.9396 mL 13.8792 mL 34.6981 mL
10 mM 0.6940 mL 3.4698 mL 6.9396 mL 17.3491 mL
15 mM 0.4626 mL 2.3132 mL 4.6264 mL 11.5660 mL
20 mM 0.3470 mL 1.7349 mL 3.4698 mL 8.6745 mL
25 mM 0.2776 mL 1.3879 mL 2.7758 mL 6.9396 mL
30 mM 0.2313 mL 1.1566 mL 2.3132 mL 5.7830 mL
H2O 40 mM 0.1735 mL 0.8675 mL 1.7349 mL 4.3373 mL
50 mM 0.1388 mL 0.6940 mL 1.3879 mL 3.4698 mL
60 mM 0.1157 mL 0.5783 mL 1.1566 mL 2.8915 mL
80 mM 0.0867 mL 0.4337 mL 0.8675 mL 2.1686 mL
100 mM 0.0694 mL 0.3470 mL 0.6940 mL 1.7349 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Sodium benzoate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sodium532-32-1Biochemical Assay ReagentsNF-κBEnvironmental PollutantsApoptosisNuclear factor-κBNuclear factor-kappaBEnvironmental Contaminantspharmaceutical excipientpharmaceutical auxiliariepharmaceutical ingredientsinactive ingredientsstabilitysolubilityprocessabilityabsorptiondistributionmetabolismand elimination (ADME)Inhibitorinhibitorinhibit

최근 본 상품:

온라인 문의

Your information is safe with us. * Required Fields.

상품명

  

Requested Quantity *

고객명 *

 

호칭

메일주소 *

 

전화번호 *

Department

 

회사명 *

City

도

Country or Region *

      

비고

대량구매 문의

Inquiry Information

상품명:
Sodium benzoate
Cat. No.:
HY-Y1316
수량:
MCE Japan Authorized Agent:

고객리뷰

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

상품명

  

Lot #

고객명 *

 

메일주소 *

전화번호

 

Department *

회사명 *

 

Country or Region *

비고

SAFETY DATA SHEET (SDS)

English - EN (396 KB) Français - FR (396 KB) Deutsch - DE (396 KB) Norwegian - NO (396 KB) Español - ES (396 KB) Swedish - SV (396 KB) Italian - IT (396 KB) Korean - KR (396 KB) Portuguese - PT (396 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.