2. Others NF-κB Apoptosis
  3. Biochemical Assay Reagents NF-κB Environmental Pollutants Apoptosis
  4. Sodium benzoate

安息香酸ナトリウム  (Synonyms: Sodium benzoate)

製品番号: HY-Y1316 純度: 99.87%
COA 取扱説明書 Technical Support

Sodium benzoate is an orally active pharmaceutical excipient, such as an antibacterial agent, preservative, lubricant, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs.Sodium benzoate activates NF-κB and induces Apoptosis. Sodium benzoate induces immune suppression and produces reproductively toxic. Sodium benzoate can be used for colon cancer and immune disease research.

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Sodium benzoate

安息香酸ナトリウム 構造式

CAS 番号 : 532-32-1

容量 価格（税別） 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 27 在庫あり
Solution
10 mM * 1 mL in DMSO USD 27 在庫あり
Solid
100 mg $25 在庫あり
500 mg $50 在庫あり
1 g $68 在庫あり
5 g $118 在庫あり
10 g $155 在庫あり
25 g $264 在庫あり
50 g $344 在庫あり
100 g $447 在庫あり
> 100 g   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

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Based on 2 publication(s) in Google Scholar

Other Forms of Sodium benzoate:

安息香酸ナトリウム 関連抗体

Top Publications Citing Use of Products

NF-κB アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示
NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

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製品説明

Sodium benzoate is an orally active pharmaceutical excipient, such as an antibacterial agent, preservative, lubricant, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs.Sodium benzoate activates NF-κB and induces Apoptosis. Sodium benzoate induces immune suppression and produces reproductively toxic. Sodium benzoate can be used for colon cancer and immune disease research[1][2][3][4][5].

体外実験

Sodium benzoate (0.125-3 mg/mL, 48 h) does not completely protect the PC12 cells to aluminum-induced free radicals toxicity[4].
Sodium benzoate (0-2500 mg/mL, 72 h) affects the functional and activation status of splenocytes at non cytotoxic dose, with inducing immune suppression[5].
Sodium benzoate (0.39-200 mM, 24 h) activates NF-κB and induces apoptosis in HCT116 cells[6].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

安息香酸ナトリウム 関連抗体
体内実験

Sodium benzoate (125-500 ppm, diet, 8 weeks) affects body weight, food intake, lipid profile and biochemical indices of kidney and liver function in mice[2].
Sodium benzoate (0-1000 mg/kg, p.o., 90 consecutive days) is dose-dependently reproductively toxic to male rats, with reducing sperm parameters, alters plasma levels of sex hormones[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

144.10

分子式

C7H5NaO2
CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

O=C(O[Na])C1=CC=CC=C1
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Store at room temperature 3 years

*In solvent : -80°C, 6 months; -20°C, 1 month (Store at room temperature 3 years)
溶剤 & 溶解度
体外: 

H2O : ≥ 100 mg/mL (693.96 mM)

DMSO : 5 mg/mL (34.70 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.9396 mL 34.6981 mL 69.3962 mL
5 mM 1.3879 mL 6.9396 mL 13.8792 mL
10 mM 0.6940 mL 3.4698 mL 6.9396 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
純度とドキュメンテーション

純度: 99.87%

COA (249 KB) HNMR (128 KB) RP-HPLC (255 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 6.9396 mL 34.6981 mL 69.3962 mL 173.4906 mL
5 mM 1.3879 mL 6.9396 mL 13.8792 mL 34.6981 mL
10 mM 0.6940 mL 3.4698 mL 6.9396 mL 17.3491 mL
15 mM 0.4626 mL 2.3132 mL 4.6264 mL 11.5660 mL
20 mM 0.3470 mL 1.7349 mL 3.4698 mL 8.6745 mL
25 mM 0.2776 mL 1.3879 mL 2.7758 mL 6.9396 mL
30 mM 0.2313 mL 1.1566 mL 2.3132 mL 5.7830 mL
H2O 40 mM 0.1735 mL 0.8675 mL 1.7349 mL 4.3373 mL
50 mM 0.1388 mL 0.6940 mL 1.3879 mL 3.4698 mL
60 mM 0.1157 mL 0.5783 mL 1.1566 mL 2.8915 mL
80 mM 0.0867 mL 0.4337 mL 0.8675 mL 2.1686 mL
100 mM 0.0694 mL 0.3470 mL 0.6940 mL 1.7349 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Sodium benzoate Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sodium532-32-1Biochemical Assay ReagentsNF-κBEnvironmental PollutantsApoptosisNuclear factor-κBNuclear factor-kappaBEnvironmental Contaminantspharmaceutical excipientpharmaceutical auxiliariepharmaceutical ingredientsinactive ingredientsstabilitysolubilityprocessabilityabsorptiondistributionmetabolismand elimination (ADME)Inhibitorinhibitorinhibit

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