2. GPCR/G Protein MAPK/ERK Pathway
  3. SOS1 Ras
  4. SOS1-IN-13

SOS1-IN-13 is a potent son of sevenless homolog 1 (SOS1) inhibitor with IC50s of 6.5 nM and 327 nM for SOS1 and pERK, respectively. SOS1-IN-13 can be used for researching anticancer.

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SOS1-IN-13

SOS1-IN-13 화학구조

CAS No. : 2654741-45-2

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SOS1-IN-13 Related Antibodies

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제품 설명

SOS1-IN-13 is a potent son of sevenless homolog 1 (SOS1) inhibitor with IC50s of 6.5 nM and 327 nM for SOS1 and pERK, respectively. SOS1-IN-13 can be used for researching anticancer[1].

IC50 & Target

IC50: 6.5 nM (SOS1), 327 nM (pERK)[1]
Cellular Effect
Cell Line Type Value Description References
MKN-1 IC50
195 nM
Compound: 16
Antiproliferative activity against human MKN-1 cells assessed as reduction in cell viability measured for 48 hrs by CCK-8 assay
Antiproliferative activity against human MKN-1 cells assessed as reduction in cell viability measured for 48 hrs by CCK-8 assay
[PMID: 38430853]
분자량

405.41

화학식

C21H22F3N3O2
CAS No.
SMILES

COC1=C(C=C2C(C(C)=NN=C2N[C@@H](C3=CC=CC(C(F)(F)F)=C3C)C)=C1)OC
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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SOS1-IN-13 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SOS1-IN-132654741-45-2SOS1RasRas/Rac guanine nucleotide exchange factor 1AnticancerInhibitorinhibitorinhibit

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상품명:
SOS1-IN-13
Cat. No.:
HY-144967
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