2. GPCR/G Protein
  3. Adenosine Receptor
  4. Sulmazole

Sulmazole is a cardiotonic agent. Sulmazole has competitive inhibitory for A1 adenosine receptor. Sulmazole can improve cardiac index and reduce pulmonary capillary wedge pressure.

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Sulmazole

Sulmazole Chemical Structure

CAS No. : 73384-60-8

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Sulmazole Related Antibodies

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Adenosine A1 receptor (A1R) Adenosine A2A receptor (A2AR) Adenosine A2B receptor (A2BR) Adenosine A3 receptor (A3R)

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Description

Sulmazole is a cardiotonic agent. Sulmazole has competitive inhibitory for A1 adenosine receptor. Sulmazole can improve cardiac index and reduce pulmonary capillary wedge pressure[1].

In Vitro

Sulmazole has competitive inhibitory for A1 adenosine receptors[1].
Sulmazole attenuates the capacity of GTP to inhibit adenylate cyclase activity and covalent modification of Gi by pertussis toxin treatment abolishes the capacity of sulmazole to mediate stimulation[1].
Sulmazole has stimulatory effect on adenylate cyclase activity in pertussis toxin-treated membranes[1].
Sulmazole mediates increases in cAMP accumulation by mechanisms other than phosphodiesterase inhibition, including A1 adenosine receptor antagonism and inhibition of Gi function[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Sulmazole Related Antibodies
Masse moléculaire

287.34

Formule

C14H13N3O2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(C)C1=CC=C(C(OC)=C1)C2=NC3=NC=CC=C3N2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Pureté et documentation
Références
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Sulmazole Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sulmazole73384-60-8Adenosine ReceptorP1 receptorcardiotonicinhibitoryA1 adenosine receptorcardiac indexpulmonary capillary wedge pressureInhibitorinhibitorinhibit

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