2. Antibody-drug Conjugate/ADC Related PROTAC
  3. ADC Linker PROTAC Linkers
  4. Tetraethylene glycol monotosylate

Tetraethylene glycol monotosylate  (Synonyms: Tos-PEG4)

Art. -Nr.: HY-41541 Reinheit: 97.0%
COA
SDS
Handling Instructions Technical Support

Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Tetraethylene glycol monotosylate also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.

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Tetraethylene glycol monotosylate

Tetraethylene glycol monotosylate Chemische Struktur

CAS. Nr. : 77544-60-6

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Tetraethylene glycol monotosylate Related Antibodies

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Alle ADC Linker Isoform-spezifische Produkte anzeigen:

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Cleavable Linker Non-cleavable Linker Acid Cleavable Linker Disulfide Cleavable Linker Protease Cleavable Linker Glycosidase Cleavable Linker Phosphatase Cleavable Linker

Alle PROTAC Linkers Isoform-spezifische Produkte anzeigen:

Alle Isoformen anzeigen
PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

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Beschreibung

Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetraethylene glycol monotosylate also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.

IC50 & Target[1]

Cleavable Linker

 

PEGs

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Tetraethylene glycol monotosylate Related Antibodies
Molekulargewicht

348.41

Formel

C15H24O7S
CAS. Nr.
Appearance

Viscous Liquid

Color

Colorless to light yellow

SMILES

OCCOCCOCCOCCOS(C1=CC=C(C)C=C1)(=O)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reinheit & Dokumentation

Purity: 97.0%

SDS (641 KB)

COA (242 KB) HNMR (119 KB)

Handling Instructions (2659 KB)
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Tetraethylene glycol monotosylate Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tetraethylene glycol monotosylate77544-60-6Tos-PEG4ADC LinkerPROTAC LinkersAntibody-drug conjugates linkerADCLinkerInhibitorinhibitorinhibit

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SAFETY DATA SHEET (SDS)

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