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TIS108 is a triazole-type strigolactone biosynthesis inhibitor. TIS108 inhibits Arabidopsis embryogenesis and root hair growth, and promotes shoot branching. TIS108 can also increase the gibberellin content in Gastrodia elata. TIS108 can be used in the research of plant growth and development as well as plant responses to the environment.

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TIS108

TIS108 構造式

CAS 番号 : 1315459-30-3

容量 価格（税別） 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 127 在庫あり
Solution
10 mM * 1 mL in DMSO USD 127 在庫あり
Solid
5 mg $116 在庫あり
10 mg $186 在庫あり
25 mg $372 在庫あり
50 mg $595 在庫あり
100 mg $950 在庫あり
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TIS108 関連抗体

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Brassinolide Gibberellins

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製品説明

TIS108 is a triazole-type strigolactone biosynthesis inhibitor. TIS108 inhibits Arabidopsis embryogenesis and root hair growth, and promotes shoot branching. TIS108 can also increase the gibberellin content in Gastrodia elata. TIS108 can be used in the research of plant growth and development as well as plant responses to the environment[1][2][3].

体外実験

TIS108 (0-1.6 μM; 0-14 days) can inhibit the number of somatic embryos formed in Arabidopsis explants, partially reverse the up-regulating effect of GR24 (HY-129038) on the expression of ARF5, ARF8, ARF10, and ARF16 genes, and simultaneously affect the expression of WUS and SERK1 genes[1].
TIS108 (1-3 μM) can increase the number of shoot branches, inhibit root hair elongation, and promote the expression of MAX3 and MAX4 in wild-type Arabidopsis[2].
TIS108 (10 μM; 14 days) can significantly increase the gibberellin content and reduce the level of GeCYP714A1 in Gastrodia elata tubers[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

TIS108 関連抗体

Real Time qPCR[3]

Cell Line: Gastrodia elata tubers
Concentration: 10 μM
Incubation Time: 14 days
Result: Inhibited the level of GeCYP714A1.
分子量

335.40

分子式

C20H21N3O2
CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC=CC=C1)C(N2N=CN=C2)CCCCOC3=CC=CC=C3
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : ≥ 125 mg/mL (372.69 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9815 mL 14.9076 mL 29.8151 mL
5 mM 0.5963 mL 2.9815 mL 5.9630 mL
10 mM 0.2982 mL 1.4908 mL 2.9815 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

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純度とドキュメンテーション

純度: 99.92%

COA (246 KB) HNMR (258 KB) LCMS (94 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9815 mL 14.9076 mL 29.8151 mL 74.5379 mL
5 mM 0.5963 mL 2.9815 mL 5.9630 mL 14.9076 mL
10 mM 0.2982 mL 1.4908 mL 2.9815 mL 7.4538 mL
15 mM 0.1988 mL 0.9938 mL 1.9877 mL 4.9692 mL
20 mM 0.1491 mL 0.7454 mL 1.4908 mL 3.7269 mL
25 mM 0.1193 mL 0.5963 mL 1.1926 mL 2.9815 mL
30 mM 0.0994 mL 0.4969 mL 0.9938 mL 2.4846 mL
40 mM 0.0745 mL 0.3727 mL 0.7454 mL 1.8634 mL
50 mM 0.0596 mL 0.2982 mL 0.5963 mL 1.4908 mL
60 mM 0.0497 mL 0.2485 mL 0.4969 mL 1.2423 mL
80 mM 0.0373 mL 0.1863 mL 0.3727 mL 0.9317 mL
100 mM 0.0298 mL 0.1491 mL 0.2982 mL 0.7454 mL
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TIS108 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TIS1081315459-30-3TIS 108TIS-108Phytohormonestrigolactoneembryogenesisepi-5DSGastrodia elataArabidopsisInhibitorinhibitorinhibit

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製品名:
TIS108
製品番号:
HY-136403
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