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  4. Trimethyl chitosan

Trimethyl chitosan  (Synonyms: N,N,N-Trimethylchitosan)

製品番号: HY-148033
COA 取扱説明書 Technical Support

Trimethyl chitosan (N,N,N-Trimethylchitosan) is a multifunctional polymer and a derivative of Chitosan (HY-B2144A). Trimethyl chitosan targets the absorption enhancing proteins of tight junctions of intestinal and mucosal epithelial cells, induces tight junction protein rearrangement, and increases intercellular permeability. Trimethyl chitosan can stimulate the activity of promoting transmembrane transport of hydrophilic drugs (such as peptides and proteins) and can be used for drug delivery and synthesis of nanoparticles.

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Trimethyl chitosan

Trimethyl chitosan 構造式

CAS 番号 : 52349-26-5

容量 価格（税別） 在庫状況 数量
>無料サンプル (0.1 - 0.2 mg)   今すぐ申し込む  
50 mg $80 在庫あり
100 mg $135 在庫あり
200 mg   お問い合わせ  
500 mg   お問い合わせ  

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Trimethyl chitosan 関連抗体

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製品説明

Trimethyl chitosan (N,N,N-Trimethylchitosan) is a multifunctional polymer and a derivative of Chitosan (HY-B2144A). Trimethyl chitosan targets the absorption enhancing proteins of tight junctions of intestinal and mucosal epithelial cells, induces tight junction protein rearrangement, and increases intercellular permeability. Trimethyl chitosan can stimulate the activity of promoting transmembrane transport of hydrophilic drugs (such as peptides and proteins) and can be used for drug delivery and synthesis of nanoparticles[1][2].

体外実験

Trimethyl chitosan (0.05-1.0% (w/v); 2-4 h) reduced transepithelial electrical resistance (TEER) in a concentration-dependent manner in Caco-2 cell monolayer experiments and significantly increased the transmembrane transport efficiency of 14C-mannitol without significantly affecting cell viability[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Trimethyl chitosan 関連抗体
CAS 番号
Appearance

Solid

Color

Off-white to light yellow

SMILES

OC[C@@H]1[C@@H](C)[C@H](O)[C@@H]([N+](C)(C)C)[C@H](OC)O1.[Cl-].[n]
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

H2O : 33.33 mg/mL (ultrasonic and warming and heat to 60°C)

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

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体内:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 10 mg/mL; Clear solution; Need ultrasonic

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Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
純度とドキュメンテーション

COA (252 KB)

取扱説明書 (2659 KB)
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Trimethyl chitosan Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Trimethyl chitosan52349-26-5N,N,N-TrimethylchitosanDrug DerivativeDrug derivativedrug deliverynanoparticleswater-solublechitosanInhibitorinhibitorinhibit

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Trimethyl chitosan
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