2. Neuronal Signaling
  3. OGT
  4. UDP-GlcNAc disodium

UDP-GlcNAc (disodium)  (Synonyms: UDP-α-D-N-Acetylglucosamine (disodium))

製品番号: HY-112174 純度: 99.92%
COA 取扱説明書 Technical Support

UDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) is a donor substrate of O-GlcNAc transferase (OGT).

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CAS 番号 : 91183-98-1

容量 価格（税別） 在庫状況 数量
5 mg $80 在庫あり
10 mg $136 在庫あり
25 mg $240 在庫あり
50 mg $320 在庫あり
100 mg $430 在庫あり
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カスタマーレビュー

Based on 6 publication(s) in Google Scholar

Other Forms of UDP-GlcNAc disodium:

UDP-GlcNAc (disodium) 関連抗体

Top Publications Citing Use of Products

    UDP-GlcNAc disodium purchased from MedChemExpress. Usage Cited in: Cancer Res. 2025 Mar 14;85(6):1113-1129.  [Abstract]

    MTHFD2 knockdown cells and control cells were treated with sunitinib (10 μM) and UDP-GlcNAc (10 μM) for 48 hours. Cell viability (n = 3).

    UDP-GlcNAc disodium purchased from MedChemExpress. Usage Cited in: Cancer Res. 2025 Mar 14;85(6):1113-1129.  [Abstract]

    MTHFD2 knockdown cells and control cells were treated with sunitinib (10 μmol/L) and UDP-GlcNAc (10 μmol/L) for 48 hours. Cell apoptosis (n = 3) were used to assess the killing capacity of sunitinib. PI, propidium iodide. G, Relative levels of metabolites in MTHFD2 knockdown cells measured by untargeted metabolomics (n = 6). F6P, fructose-6-phosphate;

    UDP-GlcNAc disodium purchased from MedChemExpress. Usage Cited in: Cancer Res. 2025 Mar 14;85(6):1113-1129.  [Abstract]

    Immunoblotting analysis of whole cell lysate (input) and His pull-down products derived from 786O cells transfected with indicated constructs and treated with MG132 (10 μmol/L) for 6 hours after cells were treated with or without UDP-GlcNAc (10 μM) for 24 hours. NC, negative control. The results showed that UDP-GlcNAc could reverse the increased c-MYC ubiquitination resulting from the silencing of MTHFD2 expression.

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    製品説明

    UDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) is a donor substrate of O-GlcNAc transferase (OGT).

    体外実験

    OGT is a nucleocytoplasmic glycosyltransferase (uridine diphospho-N--acetylglucosamine:polypeptide β-N-acetylglucosaminyltransferase or O-GlcNAc transferase) assigned to the GT41 family in the CAZY (Carbohydrate-Active enZYme) database. Using UDP-GlcNAc Disodium Salt (UDP-GlcNAc) as the donor substrate, this enzyme modifies thousands of proteins by adding a unique N-acetylglucosamine residue onto acceptor substrates mainly confined within cytosol and nucleus[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    UDP-GlcNAc (disodium) 関連抗体
    分子量

    651.32

    分子式

    C17H25N3Na2O17P2
    CAS 番号
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    O[C@H]1[C@H](N2C(NC(C=C2)=O)=O)O[C@H](COP(OP(O[C@@H]3[C@@H]([C@H]([C@H](O)[C@@H](CO)O3)O)NC(C)=O)(O[Na])=O)(O[Na])=O)[C@H]1O
    輸送条件

    Room temperature in continental US; may vary elsewhere.
    保管条件

    -20°C, sealed storage, away from moisture

    *The compound is unstable in solutions, freshly prepared is recommended.
    溶剤 & 溶解度
    体外: 

    H2O : 125 mg/mL (191.92 mM; Need ultrasonic)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 1.5353 mL 7.6767 mL 15.3534 mL
    5 mM 0.3071 mL 1.5353 mL 3.0707 mL
    10 mM 0.1535 mL 0.7677 mL 1.5353 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    一般には略語で表示されます：C1V1 = C2V2

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    純度とドキュメンテーション

    純度: 99.92%

    COA (252 KB) HNMR (290 KB) CNMR (442 KB) RP-HPLC (236 KB) MS (68 KB)

    取扱説明書 (2659 KB)
    参考文献

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O 1 mM 1.5353 mL 7.6767 mL 15.3534 mL 38.3836 mL
    5 mM 0.3071 mL 1.5353 mL 3.0707 mL 7.6767 mL
    10 mM 0.1535 mL 0.7677 mL 1.5353 mL 3.8384 mL
    15 mM 0.1024 mL 0.5118 mL 1.0236 mL 2.5589 mL
    20 mM 0.0768 mL 0.3838 mL 0.7677 mL 1.9192 mL
    25 mM 0.0614 mL 0.3071 mL 0.6141 mL 1.5353 mL
    30 mM 0.0512 mL 0.2559 mL 0.5118 mL 1.2795 mL
    40 mM 0.0384 mL 0.1919 mL 0.3838 mL 0.9596 mL
    50 mM 0.0307 mL 0.1535 mL 0.3071 mL 0.7677 mL
    60 mM 0.0256 mL 0.1279 mL 0.2559 mL 0.6397 mL
    80 mM 0.0192 mL 0.0960 mL 0.1919 mL 0.4798 mL
    100 mM 0.0154 mL 0.0768 mL 0.1535 mL 0.3838 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    UDP-GlcNAc disodium Related Classifications

    • Molarity Calculator

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    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    一般には略語で表示されます：C1V1 = C2V2

    濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
    × = ×
    C1   V1   C2   V2
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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    UDP-GlcNAc disodium91183-98-1UDP-α-D-N-Acetylglucosamine disodiumOGTO-linked N-acetylglucosaminyltransferaseO-GlcNAc transferaseInhibitorinhibitorinhibit

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    製品名:
    UDP-GlcNAc disodium
    製品番号:
    HY-112174
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