2. Antibody-drug Conjugate/ADC Related
  3. ADC Antibody
  4. Upifitamab

Upifitamab  (Synonyms: XMT-1535; Upinitatug)

Art. -Nr.: HY-P99229 Reinheit: 99%
COA
SDS
Technical Support

Upifitamab is a humanized monoclonal antibody targeting NaPi2b. Upifitamab can be used to synthesize ADC such as Upfitamab rilsodotin. Upfitamab rilsodotin can be used in research for solid tumors including high-grade serious epithelial ovarian, fallopian tube and primary peritoneal cancer (OC). Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).

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CAS. Nr. : 2254118-43-7

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Based on 2 publication(s) in Google Scholar

Upifitamab Spezialitätsempfehlungen:

Upifitamab Related Antibodies

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Beschreibung

Upifitamab is a humanized monoclonal antibody targeting NaPi2b. Upifitamab can be used to synthesize ADC such as Upfitamab rilsodotin. Upfitamab rilsodotin can be used in research for solid tumors including high-grade serious epithelial ovarian, fallopian tube and primary peritoneal cancer (OC). Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001)[1].

Isotype

Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity

Human
IC50 & Target

NaPi2b/SLC34A2
In Vitro

Upifitamab is the monoclonal antibody part of the ADC Upfitamab rilsodotin, which can be used in solid tumor research including high-grade serious epithelial ovarian, fallopian tube and primary peritoneal cancer (OC)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Upifitamab Related Antibodies
Klinische Studie
Gene ID

10568  [NCBI]

Accession
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Molekulargewicht

145.06 kDa

CAS. Nr.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Upifitamab]
Versand

Shipping with dry ice.
Formulation

Please refer to the lot-specific COA for specific buffer information.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • IgG1-kappa
Reinheit & Dokumentation

Purity: 99%

SDS (251 KB)

COA (232 KB) SDS-PAGE (101 KB) SEC-HPLC (137 KB)

Inhibitory Antibodies User Guide (603 KB)
Verweise
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Upifitamab Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Upifitamab2254118-43-7XMT-1535 UpinitatugXMT1535XMT 1535ADC AntibodyADCnaked antibodyupifitamab rilsodotinovarian cancerInhibitorinhibitorinhibit

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SAFETY DATA SHEET (SDS)

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