2. Anti-infection
  3. CMV
  4. Valganciclovir

Valganciclovir is an orally active antiviral agent. Valganciclovir can inhibit the growth of adenoviruses and have a protective effect on immunosuppressed hamsters. Valganciclovir can be used for the research of Cytomegalovirus.

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Valganciclovir

Valganciclovir Estructura química

No. CAS : 175865-60-8

Tamaño Precio Stock Cantidad
5 mg Obtener un presupuesto 3 - 5 weeks 2 - 4 weeks 4 - 6 weeks 2 - 4 weeks
10 mg Obtener un presupuesto 3 - 5 weeks 2 - 4 weeks 4 - 6 weeks 2 - 4 weeks
25 mg Obtener un presupuesto 3 - 5 weeks 2 - 4 weeks 4 - 6 weeks 2 - 4 weeks
50 mg Obtener un presupuesto 3 - 5 weeks 2 - 4 weeks 4 - 6 weeks 2 - 4 weeks
100 mg Obtener un presupuesto 3 - 5 weeks 2 - 4 weeks 4 - 6 weeks 2 - 4 weeks
200 mg   Obtener un presupuesto  
500 mg   Obtener un presupuesto  
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Other Forms of Valganciclovir:

Valganciclovir Related Antibodies

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Descripciòn

Valganciclovir is an orally active antiviral agent. Valganciclovir can inhibit the growth of adenoviruses and have a protective effect on immunosuppressed hamsters. Valganciclovir can be used for the research of Cytomegalovirus[1][2][3].

In Vitro

Valganciclovir (500 μM, 5-7 days) inhibits the growth of human adenoviruses (Ads) in A549 cells[1].
Valganciclovir (0.003-10 mM, 10 min) with ganciclovir (HY-13637) inhibits the uptake of glycylsarcosine in Caco-2 cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Valganciclovir Related Antibodies

Cell Viability Assay[1]

Cell Line: A549 cells
Concentration: 500 μM
Incubation Time: 5 days, 7days
Result: Showed EC50 values ranged from 120.5 μM (Ad4) to 244.4 μM (Ad6).
Showed IC50 values was calculated to be 11.74 mM at 7 days post-infection.
In Vivo

Valganciclovir (200 mg/kg, Oral gavage, twice daily for16 days) protects immunosuppressed hamsters challenged intravenously with adenovirus type 5 (Ad5)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Immunosuppressed hamsters[1]
Dosage: 200 mg/kg
Administration: Oral gavage (p.o.)
Result: Resulted in significantly smaller magnitude of weight loss for all groups.
Reduced the liver pathology.
Ensayo clínico
Peso molecular

354.36

Fòrmula

C14H22N6O5
No. CAS
SMILES

N[C@@H](C(C)C)C(OCC(OCN1C=NC2=C1N=C(N)NC2=O)CO)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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Valganciclovir Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Valganciclovir175865-60-8CMVCytomegalovirusA549 cellsCaco-2 cellsImmunosuppressed hamstersInhibitorinhibitorinhibit

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