Yp537 TFA (Synonyms: Anti-estrogen TFA)

Cat. No.: HY-P3833A: Data Sheet
SDS
Handling Instructions
FAQs
Technical Support

Yp537 TFA is an estrogen receptor (ER) inhibitor that blocks dimerization of the human estrogen receptor.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Yp537 TFA 화학구조

사이즈	가격	재고
5 mg		Ask For Quote & Lead Time
10 mg		Ask For Quote & Lead Time

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

Other Forms of Yp537 TFA:

Yp537 견적 받기

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•Related Small Molecules:

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View All Estrogen Receptor/ERR Isoform Specific Products:

View All Isoforms

Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

Biological Activity
순도&문서
References
고객리뷰

제품 설명

Yp537 TFA is an estrogen receptor (ER) inhibitor that blocks dimerization of the human estrogen receptor^[1].

In Vitro

Yp537 TFA (5-50 μM; 1 h) abolishes the formation of the hER-ERE complex. And dose not inhibit the formation of the STAT1-serum-induced element complex^[1].
Yp537 TFA binds to a SH2-like domain, and interferes with the SH2-like phosphopeptide coupling mechanism between hER monomers^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

1584.65

화학식

C₆₆H₁₀₅F₃N₁₃O₂₄PS

Appearance

Solid

Color

White to off-white

Sequence

Cys-Asn-Val-Val-Pro-Leu-{Tyr(PO3H2)}-Asp-Leu-Leu-Leu-Glu

Sequence Shortening

CNVVPL-{Tyr(PO3H2)}-DLLLE

선적

Room temperature in continental US; may vary elsewhere.

보관

Sealed storage, away from moisture and light, under nitrogen

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

순도&문서

Data Sheet (258 KB) SDS (252 KB) Handling Instructions (2659 KB)

References

[1]. Arnold SF, et al. An antiestrogen: a phosphotyrosyl peptide that blocks dimerization of the human estrogen receptor. Proc Natl Acad Sci U S A. 1995 Aug 1;92(16):7475-9. [Content Brief]

Yp537 TFA Related Classifications

Endocrinology

몰농도 계산기
농도 희석 계산기

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Yp537Anti-estrogenYp 537Yp-537Estrogen Receptor/ERRhER-EREInhibitorinhibitorinhibit

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