2. Metabolic Enzyme/Protease
  3. Liposome Endogenous Metabolite
  4. 1,3-Diolein

1,3-Diolein is a phospholipid compound that has the activity of regulating cell membrane fluidity and signal transduction. 1,3-Diolein is widely used in cell biology research to study lipid-mediated signal transduction pathways and membrane protein interactions. 1,3-Diolein can also serve as a functional carrier in compound delivery systems to help improve the bioavailability of compounds.

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1,3-Diolein

1,3-Diolein 構造式

CAS 番号 : 2465-32-9

容量 価格（税別） 在庫状況 数量
5 mg $40 在庫あり
10 mg $60 在庫あり
50 mg   お問い合わせ  
100 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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Other Forms of 1,3-Diolein:

1,3-Diolein 関連抗体

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製品説明

1,3-Diolein is a phospholipid compound that has the activity of regulating cell membrane fluidity and signal transduction. 1,3-Diolein is widely used in cell biology research to study lipid-mediated signal transduction pathways and membrane protein interactions. 1,3-Diolein can also serve as a functional carrier in compound delivery systems to help improve the bioavailability of compounds.

Cellular Effect
Cell Line Type Value Description References
A549 IC50
> 10 μM
Compound: 7
Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
[PMID: 28445049]
HepG2 IC50
> 10 μM
Compound: 7
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
[PMID: 28445049]
MDA-MB-231 IC50
> 10 μM
Compound: 7
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay
[PMID: 28445049]
Neutrophil IC50
> 10 μM
Compound: 7
Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLF/CB-induced elastase release by measuring degranulation of azurophilic granules using MeOSuc-Ala-Ala-ProVal-p-nitroanilide as substrate preincubated for 5 mins followed by CB/fMLF stimulation
Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLF/CB-induced elastase release by measuring degranulation of azurophilic granules using MeOSuc-Ala-Ala-ProVal-p-nitroanilide as substrate preincubated for 5 mins followed by CB/fMLF stimulation
[PMID: 28445049]
Neutrophil IC50
> 10 μM
Compound: 7
Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLF/CB-induced superoxide anion generation preincubated for 5 mins followed by CB stimulation for 3 mins and subsequent fMLF stimulation for 10 mins by spectrophotometric method
Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLF/CB-induced superoxide anion generation preincubated for 5 mins followed by CB stimulation for 3 mins and subsequent fMLF stimulation for 10 mins by spectrophotometric method
[PMID: 28445049]
分子量

620.99

分子式

C39H72O5
CAS 番号
Appearance

Viscous Liquid

Color

Colorless to light yellow

SMILES

CCCCCCCC/C=C\CCCCCCCC(OCC(O)COC(CCCCCCC/C=C\CCCCCCCC)=O)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
体外: 

DMSO : 100 mg/mL (161.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6103 mL 8.0517 mL 16.1033 mL
5 mM 0.3221 mL 1.6103 mL 3.2207 mL
10 mM 0.1610 mL 0.8052 mL 1.6103 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6103 mL 8.0517 mL 16.1033 mL 40.2583 mL
5 mM 0.3221 mL 1.6103 mL 3.2207 mL 8.0517 mL
10 mM 0.1610 mL 0.8052 mL 1.6103 mL 4.0258 mL
15 mM 0.1074 mL 0.5368 mL 1.0736 mL 2.6839 mL
20 mM 0.0805 mL 0.4026 mL 0.8052 mL 2.0129 mL
25 mM 0.0644 mL 0.3221 mL 0.6441 mL 1.6103 mL
30 mM 0.0537 mL 0.2684 mL 0.5368 mL 1.3419 mL
40 mM 0.0403 mL 0.2013 mL 0.4026 mL 1.0065 mL
50 mM 0.0322 mL 0.1610 mL 0.3221 mL 0.8052 mL
60 mM 0.0268 mL 0.1342 mL 0.2684 mL 0.6710 mL
80 mM 0.0201 mL 0.1006 mL 0.2013 mL 0.5032 mL
100 mM 0.0161 mL 0.0805 mL 0.1610 mL 0.4026 mL
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1,3-Diolein Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1,3-Diolein2465-32-9LiposomeEndogenous MetaboliteInhibitorinhibitorinhibit

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製品名:
1,3-Diolein
製品番号:
HY-W587552
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