3-Iodothyronamine hydrochloride

製品番号: HY-135065 純度: 99.5%: Data Sheet SDS COA 取扱説明書
FAQs
Technical Support

3-Iodothyronamine (hydrochloride) is an endogenous and rapid-acting derivative of thyroid hormone. 3-Iodothyronamine potently activates an orphan G protein-coupled receptor in vitro (TAAR1) and induced hypothermia in vivo on a rapid time scale. 3-Iodothyronamine can be used for the research of congestive heart failure.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

3-Iodothyronamine hydrochloride 構造式

CAS 番号 : 788824-64-6

容量	価格（税別）	在庫状況	数量
5 mg	$200	在庫あり	Estimated Time of Arrival: December 31
10 mg	$340	在庫あり	Estimated Time of Arrival: December 31
25 mg	$750	在庫あり	Estimated Time of Arrival: December 31
50 mg		お問い合わせ
100 mg		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 0 publication(s) in Google Scholar

Other Forms of 3-Iodothyronamine hydrochloride:

3-Iodothyronamine-d₄ hydrochloride 在庫あり
3-Iodothyronamine hydrochloride-13C6 お問い合わせ

おすすめ

•関連スクリーニングライブラリ:

•関連小分子:

•関連タンパク質:

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	314 nM Compound: 1	Activity at mouse TAAR1 expressed in HEK293 cells assessed as cAMP production Activity at mouse TAAR1 expressed in HEK293 cells assessed as cAMP production	[PMID: 17497842]
HEK293	EC₅₀	33 nM Compound: 1	Activity at rat TAAR1 expressed in HEK293 cells assessed as cAMP production Activity at rat TAAR1 expressed in HEK293 cells assessed as cAMP production	[PMID: 17497842]

分子量

391.63

分子式

C₁₄H₁₅ClINO₂

CAS 番号

788824-64-6

Appearance

Solid

Color

White to off-white

SMILES

OC1=CC=C(OC2=CC=C(CCN)C=C2I)C=C1.Cl

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶剤 & 溶解度

体外:

DMSO : 25 mg/mL (63.84 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.5534 mL	12.7672 mL	25.5343 mL
5 mM	0.5107 mL	2.5534 mL	5.1069 mL
10 mM	0.2553 mL	1.2767 mL	2.5534 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 99.5%

Select Batch:

データシート (266 KB) SDS (538 KB)

COA (244 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Hart ME, et al. Trace amine-associated receptor agonists: synthesis and evaluation of thyronamines and related analogues. J Med Chem. 2006 Feb 9;49(3):1101-12. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.5534 mL	12.7672 mL	25.5343 mL	63.8358 mL
	5 mM	0.5107 mL	2.5534 mL	5.1069 mL	12.7672 mL
	10 mM	0.2553 mL	1.2767 mL	2.5534 mL	6.3836 mL
	15 mM	0.1702 mL	0.8511 mL	1.7023 mL	4.2557 mL
	20 mM	0.1277 mL	0.6384 mL	1.2767 mL	3.1918 mL
	25 mM	0.1021 mL	0.5107 mL	1.0214 mL	2.5534 mL
	30 mM	0.0851 mL	0.4256 mL	0.8511 mL	2.1279 mL
	40 mM	0.0638 mL	0.3192 mL	0.6384 mL	1.5959 mL
	50 mM	0.0511 mL	0.2553 mL	0.5107 mL	1.2767 mL
	60 mM	0.0426 mL	0.2128 mL	0.4256 mL	1.0639 mL