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Cat. No.: HY-W755778

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3-Iodothyronamine hydrochloride-13C6

3-Iodothyronamine hydrochloride-¹³C₆ is the ¹³C-labeled 3-Iodothyronamine hydrochloride (HY-135065). 3-Iodothyronamine hydrochloride is an endogenous and rapid-acting derivative of thyroid hormone. 3-Iodothyronamine potently activates an orphan G protein-coupled receptor in vitro (TAAR1) and induced hypothermia in vivo on a rapid time scale. 3-Iodothyronamine can be used for the research of congestive heart failure.

For research use only. We do not sell to patients.

CAS No.: 2724727-67-5
Formula: C₈¹³C₆H₁₅ClINO₂
Molecular Weight:397.59

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

3-Iodothyronamine hydrochloride-13C6 Chemical Structure

CAS No.: 2724727-67-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 2724727-67-5
Unlabeled Cas 788824-64-6
Molecular Weight 397.59
Formula C₈¹³C₆H₁₅ClINO₂
SMILES

NCCC1=CC=C(C(I)=C1)O[13C]2=[13CH][13CH]=[13C]([13CH]=[13CH]2)O.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hart ME, et al. Trace amine-associated receptor agonists: synthesis and evaluation of thyronamines and related analogues. J Med Chem. 2006 Feb 9;49(3):1101-12. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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3-Iodothyronamine hydrochloride-13C6

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Biological Activity
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- Application
Chemical Information
Purity & Documentation
References

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3-Iodothyronamine hydrochloride-13C6

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

3-Iodothyronamine hydrochloride-13C6 Related Classifications

HY-W755778 Related Classifications

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