3-Iodothyronamine hydrochloride
Based on 1 Customer Validation
3-Iodothyronamine (hydrochloride) is an endogenous and rapid-acting derivative of thyroid hormone. 3-Iodothyronamine potently activates an orphan G protein-coupled receptor in vitro (TAAR1) and induced hypothermia in vivo on a rapid time scale. 3-Iodothyronamine can be used for the research of congestive heart failure.
For research use only. We do not sell to patients.
- Purity: 99.5%
- CAS No.: 788824-64-6
- Formula: C14H15ClINO2
- Molecular Weight:391.63
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
314 nM
Compound: 1
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Activity at mouse TAAR1 expressed in HEK293 cells assessed as cAMP production
Activity at mouse TAAR1 expressed in HEK293 cells assessed as cAMP production
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[PMID: 17497842] |
| HEK293 | EC50 |
33 nM
Compound: 1
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Activity at rat TAAR1 expressed in HEK293 cells assessed as cAMP production
Activity at rat TAAR1 expressed in HEK293 cells assessed as cAMP production
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[PMID: 17497842] |
Chemical Information
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CAS No. 788824-64-6
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Appearance Solid
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Molecular Weight 391.63
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Formula C14H15ClINO2
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Color White to off-white
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SMILES
OC1=CC=C(OC2=CC=C(CCN)C=C2I)C=C1.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 25 mg/mL (63.84 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (540 KB)
- English - EN (540 KB)
- Français - FR (540 KB)
- Deutsch - DE (540 KB)
- Norwegian - NO (540 KB)
- Español - ES (540 KB)
- Swedish - SV (540 KB)
- Italian - IT (540 KB)
- Korean - KR (540 KB)
- Portuguese - PT (540 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5534 mL | 12.7672 mL | 25.5343 mL | 63.8358 mL |
| 5 mM | 0.5107 mL | 2.5534 mL | 5.1069 mL | 12.7672 mL | |
| 10 mM | 0.2553 mL | 1.2767 mL | 2.5534 mL | 6.3836 mL | |
| 15 mM | 0.1702 mL | 0.8511 mL | 1.7023 mL | 4.2557 mL | |
| 20 mM | 0.1277 mL | 0.6384 mL | 1.2767 mL | 3.1918 mL | |
| 25 mM | 0.1021 mL | 0.5107 mL | 1.0214 mL | 2.5534 mL | |
| 30 mM | 0.0851 mL | 0.4256 mL | 0.8511 mL | 2.1279 mL | |
| 40 mM | 0.0638 mL | 0.3192 mL | 0.6384 mL | 1.5959 mL | |
| 50 mM | 0.0511 mL | 0.2553 mL | 0.5107 mL | 1.2767 mL | |
| 60 mM | 0.0426 mL | 0.2128 mL | 0.4256 mL | 1.0639 mL |
3-Iodothyronamine hydrochloride Related Classifications
HY-135065 Related Classifications
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