2. 疾患モデリングル製品 Antibody-drug Conjugate/ADC Related
  3. Immunology and Inflammatory Disease Models ADC Linker
  4. Hapten
  5. 6-Maleimidohexanoic acid N-hydroxysuccinimide ester

EMCS  (Synonyms: 6-Maleimidohexanoic acid N-hydroxysuccinimide ester; N-(6-マレイミドカプロイルオキシ)スクシンイミド)

製品番号: HY-78961 純度: 99.85%
COA 取扱説明書 Technical Support

6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS) is a heterobifunctional cross-linking reagent. EMCS is used as a unique and useful reagent for preparation of hapten conjugate and enzyme immunoconjugates.

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6-Maleimidohexanoic acid N-hydroxysuccinimide ester

EMCS 構造式

CAS 番号 : 55750-63-5

容量 価格（税別） 在庫状況 数量
50 mg $25 在庫あり
100 mg $35 在庫あり
500 mg $60 在庫あり
1 g $72 在庫あり
5 g $125 在庫あり
10 g $150 在庫あり
25 g $210 在庫あり
100 g $420 在庫あり
> 100 g   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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EMCS 関連抗体

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製品説明

6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS) is a heterobifunctional cross-linking reagent. EMCS is used as a unique and useful reagent for preparation of hapten conjugate and enzyme immunoconjugates[1].

IC50 & Target

Non-cleavable Linker

 

体外実験

6-Maleimidohexanoic acid N-hydroxysuccinimide ester is coupled to the peptides, and then conjugated to the Adenovirus vector containing luciferase gene as adenovirus vector carrier[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

EMCS 関連抗体
分子量

308.29

分子式

C14H16N2O6
CAS 番号
Appearance

Solid

Color

White to light yellow

SMILES

O=C(C=C1)N(CCCCCC(ON2C(CCC2=O)=O)=O)C1=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
体外: 

DMSO : ≥ 100 mg/mL (324.37 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2437 mL 16.2185 mL 32.4370 mL
5 mM 0.6487 mL 3.2437 mL 6.4874 mL
10 mM 0.3244 mL 1.6218 mL 3.2437 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション

純度: 99.94%

COA (249 KB) HNMR (132 KB) RP-HPLC (87 KB) LCMS (340 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2437 mL 16.2185 mL 32.4370 mL 81.0925 mL
5 mM 0.6487 mL 3.2437 mL 6.4874 mL 16.2185 mL
10 mM 0.3244 mL 1.6218 mL 3.2437 mL 8.1092 mL
15 mM 0.2162 mL 1.0812 mL 2.1625 mL 5.4062 mL
20 mM 0.1622 mL 0.8109 mL 1.6218 mL 4.0546 mL
25 mM 0.1297 mL 0.6487 mL 1.2975 mL 3.2437 mL
30 mM 0.1081 mL 0.5406 mL 1.0812 mL 2.7031 mL
40 mM 0.0811 mL 0.4055 mL 0.8109 mL 2.0273 mL
50 mM 0.0649 mL 0.3244 mL 0.6487 mL 1.6218 mL
60 mM 0.0541 mL 0.2703 mL 0.5406 mL 1.3515 mL
80 mM 0.0405 mL 0.2027 mL 0.4055 mL 1.0137 mL
100 mM 0.0324 mL 0.1622 mL 0.3244 mL 0.8109 mL
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6-Maleimidohexanoic acid N-hydroxysuccinimide ester Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6-Maleimidohexanoic acid N-hydroxysuccinimide ester55750-63-5EMCSADC LinkerAntibody-drug conjugates linkeraminosulfhydrylgroupscross-linkingreagentenzymeimmunoconjugateshaptenconjugateInhibitorinhibitorinhibit

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製品名:
6-Maleimidohexanoic acid N-hydroxysuccinimide ester
製品番号:
HY-78961
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