6-Me-ATP trisodium solution (100 mM) (Synonyms: N6-Methyl-ATP trisodium solution (100 mM))

Art. -Nr.: HY-134393B Reinheit: 99.89%: Data Sheet
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6-Me-ATP (N6-Methyl-ATP) trisodium solution (100 mM) is a N⁶-modified ATP derivative. 6-Me-ATP trisodium shows excellent binding affinity to GSK3, serving as the phosphate group donor for GSK3β-catalyzed phosphorylation of its substrate peptide.

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6-Me-ATP trisodium solution (100 mM) Chemische Struktur

Größe	Preis	Verfügbarkeit
Solvent
5.9 mg (100 mM * 100 μL in Water)		Anfrage über Preis & Lieferzeit

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•Related Proteins:

Alle GSK-3 Isoform-spezifische Produkte anzeigen:

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GSK-3 GSK-3α GSK-3β

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Beschreibung	6-Me-ATP (N6-Methyl-ATP) trisodium solution (100 mM) is a N⁶-modified ATP derivative. 6-Me-ATP trisodium shows excellent binding affinity to GSK3, serving as the phosphate group donor for GSK3β-catalyzed phosphorylation of its substrate peptide^[1].
Molekulargewicht	587.15
Formel	C₁₁H₁₅N₅Na₃O₁₃P₃
Appearance	Liquid
Color	Colorless to light yellow
SMILES	O[C@H]1[C@](O[C@@H]([C@H]1O)COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)([H])N2C3=NC=NC(NC)=C3N=C2
Versand	Room temperature in continental US; may vary elsewhere.
Speicherung	Solution, -20°C, 2 years
Lösungsmittel & Löslichkeit	In Vitro: H₂O : 62.5 mg/mL (106.45 mM; Need ultrasonic) Molaritätsrechner Verdünnungsrechner Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Mass = Concentration × Volume × Molecular Weight * Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final) This equation is commonly abbreviated as: C₁V₁ = C₂V₂ Concentration _(start) C1 × Volume _(start) V1 = Concentration _(final) C2 × Volume _(final) V2 In Vivo Dissolution Calculator Please enter the basic information of animal experiments: Dosage mg/kg Animal weight (per animal) g Dosing volume (per animal) μL Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments. Calculation results: Working solution concentration: mg/mL This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details. The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE). Tel: 609-228-6898 E-mail: [email protected] Technical Support: [email protected]
Reinheit & Dokumentation	Purity: 99.89% Select Batch: Data Sheet (270 KB) SDS (251 KB) COA (251 KB) Handling Instructions (2659 KB)
Verweise	[1]. Dong X, et al. Proteome-Wide Characterizations of N6-Methyl-Adenosine Triphosphate- and N6-Furfuryl-Adenosine Triphosphate-Binding Capabilities of Kinases. Anal Chem. 2021 Oct 5;93(39):13251-13259. [Content Brief]

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.7031 mL	8.5157 mL	17.0314 mL	42.5786 mL
	5 mM	0.3406 mL	1.7031 mL	3.4063 mL	8.5157 mL
	10 mM	0.1703 mL	0.8516 mL	1.7031 mL	4.2579 mL
	15 mM	0.1135 mL	0.5677 mL	1.1354 mL	2.8386 mL
	20 mM	0.0852 mL	0.4258 mL	0.8516 mL	2.1289 mL
	25 mM	0.0681 mL	0.3406 mL	0.6813 mL	1.7031 mL
	30 mM	0.0568 mL	0.2839 mL	0.5677 mL	1.4193 mL
	40 mM	0.0426 mL	0.2129 mL	0.4258 mL	1.0645 mL
	50 mM	0.0341 mL	0.1703 mL	0.3406 mL	0.8516 mL
	60 mM	0.0284 mL	0.1419 mL	0.2839 mL	0.7096 mL
	80 mM	0.0213 mL	0.1064 mL	0.2129 mL	0.5322 mL
	100 mM	0.0170 mL	0.0852 mL	0.1703 mL	0.4258 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

6-Me-ATP trisodium solution (100 mM) Related Classifications

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6-Me-ATP trisodium solution (100 mM)N6-Methyl-ATP trisodium solution (100 mM)GSK-3Glycogen synthase kinase-3Glycogen synthase kinase 3phosphate group donorInhibitorinhibitorinhibit

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6-Me-ATP trisodium solution (100 mM) (Synonyms: N6-Methyl-ATP trisodium solution (100 mM))

Other Forms of 6-Me-ATP trisodium solution (100 mM):

6-Me-ATP trisodium solution (100 mM) Related Antibodies

Spezialitätsempfehlungen

•Related Small Molecules:

•Related Proteins:

Alle GSK-3 Isoform-spezifische Produkte anzeigen:

Biologische Aktivität

Reinheit & Dokumentation

Verweise

Kundenbewertung

Molaritätsrechner

Verdünnungsrechner