1. GPCR/G Protein
  2. Endothelin Receptor

BQ-123 (Synonyms: BQ 123; BQ123)

Cat. No.: HY-12378 Purity: 98.39%
Data Sheet SDS Handling Instructions

BQ-123 is an ETA endothelin receptor antagonist (Ki values are 1.4 and 1500 nM at ETA and ETB receptors respectively) .

For research use only. We do not sell to patients.
BQ-123 Chemical Structure

BQ-123 Chemical Structure

CAS No. : 136553-81-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO $537 In-stock
1 mg $100 In-stock
5 mg $400 In-stock
10 mg $700 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Description

BQ-123 is an ETA endothelin receptor antagonist (Ki values are 1.4 and 1500 nM at ETA and ETB receptors respectively) . 1) Reduces ischemia-induced ventricular arrhythmias in a rat model. 2) BQ-123 prevents LPS-induced preterm birth in mice via the induction of uterine and placental IL-10. 3) The reference for animal injections is 6.7 mg/kg. 4) BQ-123 decreased IL-1β and TNFα in the placenta while also decreasing transcription of ET-1 in the uterus.

References
M.Wt

610.7

Formula

C₃₁H₄₂N₆O₇

CAS No.

136553-81-6

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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BQ-123
Cat. No.:
HY-12378
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