1. Membrane Transporter/Ion Channel
  2. Sodium Channel

Benzocaine 

Cat. No.: HY-Y0258 Purity: 99.76%
Data Sheet SDS Handling Instructions

benzocaine is a common receptor with all other local anesthetics (LAs) in the voltage-gated Na+ channel. exerts an indirect action on the membrane permeability to calcium. key steps of the Ca-ATPase enzymatic cycle.

For research use only. We do not sell to patients.
Benzocaine Chemical Structure

Benzocaine Chemical Structure

CAS No. : 94-09-7

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO $50 In-stock
5 g $40 In-stock
10 g $60 In-stock
50 g   Get quote  

* Please select Quantity before adding items.

Customer Review

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

benzocaine is a common receptor with all other local anesthetics (LAs) in the voltage-gated Na+ channel. exerts an indirect action on the membrane permeability to calcium. key steps of the Ca-ATPase enzymatic cycle. In vitro: benzocaine is effective at blocking mu1-N1584A current than the wild-type current, while they are less potent at blocking mu1-F1579A current.[1] Benzocaine also interfered with the calcium transport capability by decreasing the maximal uptake (IC50 40.3 mM) without modification of the calcium affinity for the ATPase. It inhibited the phosphorylation of the enzyme, and at high benzocaine concentration. [2]

Clinical Trial
NCT Number Sponsor Condition Start Date Phase
NCT01274247 Tel-Aviv Sourasky Medical Center Neonatal Tongue-tie|Maternal Nipple Pain Upon Breastfeeding|Neonatal Latch Difficulties February 2011 Phase 1|Phase 2
NCT00846690 The University of Texas Health Science Center, Houston Dental Pain|Postoperative Pain January 2009 Phase 4
NCT01925469 University of Pennsylvania Pain Relief|Analgesia December 2011 Phase 4
NCT00474175 Wyeth is now a wholly owned subsidiary of Pfizer|Church & Dwight Company, Inc.|Consumer Healthcare Products Association Toothache May 2007 Phase 4
NCT02092454 Otic Therapy, LLC Pain|Acute Otitis Media September 2013 Phase 2
NCT01951820 University of Michigan|American Association of Endodontists Anesthesia of Mucous Membrane August 2013 Phase 4
NCT03116737 Lachlan Pharma Holdings Pain|Acute Otitis Media January 3, 2017 Phase 3
NCT02037893 Pernix Theraputics LLC Acute Otitis Media November 2013 Phase 2
NCT01429701 EMS Eczema May 2012 Phase 3
NCT02537314 Vanderbilt University Medical Center|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Obesity September 2015 Phase 1
NCT02153541 Global United Pharmaceutical Corporation Asthma July 2014 Phase 2
NCT02908620 Cetylite Industries Anesthesia December 7, 2016 Phase 2
NCT01694004 Vanderbilt University Medical Center|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The Effect of LCFA on Nutrient Absorption November 2012 Phase 1
NCT01588535 Arbor Pharmaceuticals, Inc. Pain|Otitis Media May 2012 Phase 2
NCT00716443 Galderma Laboratories, L.P. Nasolabial Folds July 2008 Phase 4
NCT00148499 Boehringer Ingelheim Pharyngitis October 2005 Phase 3
NCT01860235 Franciscan University Center Local Anesthesia|Pain, Postoperative|Self-Perception June 2010
NCT02674191 Cairo University Orthodontic Anchorage Procedures March 2016
NCT02726620 Vanderbilt University Medical Center|UMC Utrecht Hypotension January 2017
NCT01274247 Tel-Aviv Sourasky Medical Center Neonatal Tongue-tie|Maternal Nipple Pain Upon Breastfeeding|Neonatal Latch Difficulties February 2011 Phase 1|Phase 2
NCT00846690 The University of Texas Health Science Center, Houston Dental Pain|Postoperative Pain January 2009 Phase 4
NCT01925469 University of Pennsylvania Pain Relief|Analgesia December 2011 Phase 4
NCT00474175 Wyeth is now a wholly owned subsidiary of Pfizer|Church & Dwight Company, Inc.|Consumer Healthcare Products Association Toothache May 2007 Phase 4
NCT02092454 Otic Therapy, LLC Pain|Acute Otitis Media September 2013 Phase 2
NCT01951820 University of Michigan|American Association of Endodontists Anesthesia of Mucous Membrane August 2013 Phase 4
NCT03116737 Lachlan Pharma Holdings Pain|Acute Otitis Media January 3, 2017 Phase 3
NCT02037893 Pernix Theraputics LLC Acute Otitis Media November 2013 Phase 2
NCT01429701 EMS Eczema May 2012 Phase 3
NCT02537314 Vanderbilt University Medical Center|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Obesity September 2015 Phase 1
NCT02153541 Global United Pharmaceutical Corporation Asthma July 2014 Phase 2
NCT02908620 Cetylite Industries Anesthesia December 7, 2016 Phase 2
NCT01694004 Vanderbilt University Medical Center|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The Effect of LCFA on Nutrient Absorption November 2012 Phase 1
NCT01588535 Arbor Pharmaceuticals, Inc. Pain|Otitis Media May 2012 Phase 2
NCT00716443 Galderma Laboratories, L.P. Nasolabial Folds July 2008 Phase 4
NCT00148499 Boehringer Ingelheim Pharyngitis October 2005 Phase 3
NCT01860235 Franciscan University Center Local Anesthesia|Pain, Postoperative|Self-Perception June 2010
NCT02674191 Cairo University Orthodontic Anchorage Procedures March 2016
NCT02726620 Vanderbilt University Medical Center|UMC Utrecht Hypotension January 2017
View MoreCollapse
References
Molecular Weight

165.19

Formula

C₉H₁₁NO₂

CAS No.

94-09-7

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number

 

Organization name *

Country *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Benzocaine
Cat. No.:
HY-Y0258
Quantity: