Collagen proline hydroxylase inhibitor

Name: Collagen proline hydroxylase inhibitor
Brand: MedChemExpress
SKU: HY-15183
Rating: 4.5 (0 reviews)

Cat. No.: HY-15183 Pureté: 99.64%: Fiche technique
COA

SDS
Instruction de manipulation
FAQs
Technical Support

Collagen proline hydroxylase inhibitor is a collagen proline hydroxylase inhibitor, which can be used as an anti-fibrotic agent.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Collagen proline hydroxylase inhibitor Chemical Structure

CAS No. : 223666-07-7

Size	Stock	Quantité
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	En stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	En stock	Estimated Time of Arrival: December 31
Solid
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
25 mg	En stock	Estimated Time of Arrival: December 31
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	En stock	Estimated Time of Arrival: December 31
200 mg	Obtenir un devis
500 mg	Obtenir un devis

or Bulk Inquiry

* Veuillez sélectionner la quantité avant d'ajouter des articles.

This product is a controlled substance and not for sale in your territory.

Avis client

Based on 1 Customer Validation

Recommandations en vedette

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Activité biologique
Pureté et documentation
Références
Avis client

Description

Collagen proline hydroxylase inhibitor is a collagen proline hydroxylase inhibitor, which can be used as an anti-fibrotic agent^[1].

In Vitro

Collagen proline hydroxylase inhibitors can be used in the research of diseases such as hepatic fibrosis, pulmonary fibrosis, myocardial fibrosis, and postoperative scars^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Masse moléculaire

354.36

Formule

C₁₈H₁₈N₄O₄

CAS No.

223666-07-7

Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C1C([N+]([O-])=O)=CNC2=C1C=CC3=C2N=CC(C(N(CC)CCC)=O)=C3

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	2 years
	-20°C	1 year

Solvant et solubilité

In Vitro:

DMSO : 13.15 mg/mL (37.11 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.8220 mL	14.1099 mL	28.2199 mL
5 mM	0.5644 mL	2.8220 mL	5.6440 mL
10 mM	0.2822 mL	1.4110 mL	2.8220 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Calculateur de molarité
Calculateur de dilution

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Pureté et documentation

Purity: 99.64%

Select Batch:

Fiche technique (270 KB) SDS (251 KB)

COA (247 KB) HNMR (274 KB) LCMS (97 KB)

Instruction de manipulation (2659 KB)

Références

[1]. Philip Neil Edwards, et al. Preparation of phenanthrolinones as antifibroproliferatives. World Intellectual Property Organization, WO9921860 A1. 1999-05-06.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.8220 mL	14.1099 mL	28.2199 mL	70.5497 mL
	5 mM	0.5644 mL	2.8220 mL	5.6440 mL	14.1099 mL
	10 mM	0.2822 mL	1.4110 mL	2.8220 mL	7.0550 mL
	15 mM	0.1881 mL	0.9407 mL	1.8813 mL	4.7033 mL
	20 mM	0.1411 mL	0.7055 mL	1.4110 mL	3.5275 mL
	25 mM	0.1129 mL	0.5644 mL	1.1288 mL	2.8220 mL
	30 mM	0.0941 mL	0.4703 mL	0.9407 mL	2.3517 mL