Collagen proline hydroxylase inhibitor

Name: Collagen proline hydroxylase inhibitor
Brand: MedChemExpress
SKU: HY-15183
Rating: 4.5 (0 reviews)

Cat. No.: HY-15183 Purity: 99.64%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Collagen proline hydroxylase inhibitor is a collagen proline hydroxylase inhibitor, which can be used as an anti-fibrotic agent.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Collagen proline hydroxylase inhibitor 화학구조

CAS No. : 223666-07-7

사이즈	재고	수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	해외재고보유	Estimated Time of Arrival: December 31
Solid
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
25 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	해외재고보유	Estimated Time of Arrival: December 31
100 mg	해외재고보유	Estimated Time of Arrival: December 31
200 mg	견적 받기
500 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

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•Related Small Molecules:

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

Collagen proline hydroxylase inhibitor is a collagen proline hydroxylase inhibitor, which can be used as an anti-fibrotic agent^[1].

In Vitro

Collagen proline hydroxylase inhibitors can be used in the research of diseases such as hepatic fibrosis, pulmonary fibrosis, myocardial fibrosis, and postoperative scars^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

354.36

화학식

C₁₈H₁₈N₄O₄

CAS No.

223666-07-7

Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C1C([N+]([O-])=O)=CNC2=C1C=CC3=C2N=CC(C(N(CC)CCC)=O)=C3

선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	2 years
	-20°C	1 year

용액&용해도

In Vitro:

DMSO : 13.15 mg/mL (37.11 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.8220 mL	14.1099 mL	28.2199 mL
5 mM	0.5644 mL	2.8220 mL	5.6440 mL
10 mM	0.2822 mL	1.4110 mL	2.8220 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 99.64%

Select Batch:

Data Sheet (270 KB) SDS (251 KB)

COA (247 KB) HNMR (274 KB) LCMS (97 KB)

Handling Instructions (2659 KB)

References

[1]. Philip Neil Edwards, et al. Preparation of phenanthrolinones as antifibroproliferatives. World Intellectual Property Organization, WO9921860 A1. 1999-05-06.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.8220 mL	14.1099 mL	28.2199 mL	70.5497 mL
	5 mM	0.5644 mL	2.8220 mL	5.6440 mL	14.1099 mL
	10 mM	0.2822 mL	1.4110 mL	2.8220 mL	7.0550 mL
	15 mM	0.1881 mL	0.9407 mL	1.8813 mL	4.7033 mL
	20 mM	0.1411 mL	0.7055 mL	1.4110 mL	3.5275 mL
	25 mM	0.1129 mL	0.5644 mL	1.1288 mL	2.8220 mL
	30 mM	0.0941 mL	0.4703 mL	0.9407 mL	2.3517 mL