1. Metabolic Enzyme/Protease
    GPCR/G Protein
  2. FXR
    GPCR19
  3. INT-767

INT-767 

Cat. No.: HY-12434 Purity: >98.0%
Handling Instructions

INT-767 is a dual farnesoid X receptor/TGR5 agonist with mean EC50s of 30 and 630 nM, respectively.

For research use only. We do not sell to patients.

INT-767 Chemical Structure

INT-767 Chemical Structure

CAS No. : 1000403-03-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 990 In-stock
Estimated Time of Arrival: December 31
5 mg USD 900 In-stock
Estimated Time of Arrival: December 31
10 mg USD 1440 In-stock
Estimated Time of Arrival: December 31
50 mg USD 4320 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Top Publications Citing Use of Products

    INT-767 purchased from MCE. Usage Cited in: J Am Soc Nephrol. 2018 Nov;29(11):2658-2670.

    Western blots show that INT-767, INT-777, and INT747 upregulate AQP2 protein expression.
    • Biological Activity

    • Technical Information

    • Purity & Documentation

    • References

    Description

    INT-767 is a dual farnesoid X receptor/TGR5 agonist with mean EC50s of 30 and 630 nM, respectively.

    Storage
    Powder -20°C 3 years
      4°C 2 years
    In solvent -80°C 6 months
      -20°C 1 month
    Solvent & Solubility
    In Vitro: 

    DMSO : ≥ 205.5 mg/mL (415.44 mM)

    *"≥" means soluble, but saturation unknown.

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 2.0216 mL 10.1080 mL 20.2159 mL
    5 mM 0.4043 mL 2.0216 mL 4.0432 mL
    10 mM 0.2022 mL 1.0108 mL 2.0216 mL
    *Please refer to the solubility information to select the appropriate solvent.
    References
    Molecular Weight

    494.66

    Formula

    C₂₅H₄₃NaO₆S

    CAS No.

    1000403-03-1

    SMILES
    Shipping

    Room temperature in continental US; may vary elsewhere

    Purity: >98.0%

    • Molarity Calculator

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    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
    × = ×
    C1   V1   C2   V2

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    Inquiry Information

    Product Name:
    INT-767
    Cat. No.:
    HY-12434
    Quantity:

    INT-767

    Cat. No.: HY-12434