1. Natural Products
  2. Plants
  3. Leguminosae
  4. Caesalpinia sappan L.

Caesalpinia sappan L.

Caesalpinia sappan L. (10):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0116
    Hematoxylin 517-28-2 ≥98.0%
    Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from the logwood tree, Haematoxylon campechianum. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC50 of 1.6 µM.
  • HY-N0072
    Brazilin 474-07-7 99.26%
    Brazilin is a red dye precursor obtained from the heartwood of several species of tropical hardwoods. Brazilin inhibits the cells proliferation, promotes apoptosis, and induces autophagy through the AMPK/mTOR pathway. Brazilin shows chondroprotective and anti-inflammatory activities.
  • HY-113556
    Sappanone A 102067-84-5 98.42%
    Sappanone A is a homoisoflavanone which exhibits anti-inflammatory effects via modulation of Nrf2 and NF-κB. Sappanone can attenuate allergic airway inflammation in Ovalbumin-induced asthma.
    Sappanone A
  • HY-113573
    Protosappanin A 102036-28-2 99.98%
    Protosappanin A (PTA), an immunosuppressive ingredient and major biphenyl compound isolated from Caesalpinia sappan L, suppresses JAK2/STAT3-dependent inflammation pathway through down-regulating the phosphorylation of JAK2 and STAT3.
    Protosappanin A
  • HY-N0800
    Protosappanin B 102036-29-3 98.53%
    Protosappanin B is a phenolic compound extracted from Lignum Sappan. Anti-cancer activity. Protosappanin B induces apoptosis and causes G1 cell cycle arrest in human bladder cancer cells.
    Protosappanin B
  • HY-N9315
    Episappanol 111254-18-3
    Episappanol is a natural compound isolated from Caesalpinia sappan heartwood with anti-inflammatory activity. Episappanol significantly inhibits the IL-6 and TNF-α secretion.
  • HY-N1745A
    3-Deoxysappanchalcone 112408-67-0
    3-Deoxysappanchalcone is a naturally-occurring chalcone compound isolated from Caesalpinia sappan L.
  • HY-N9316
    3'-Deoxy-4-O-methylsappanol 112408-68-1
    3'-Deoxy-4-O-methylsappanol shows cytotoxicity against melanoma HMV II cell (IC50=50.4 μM) and has significant anti-melanogenic activities (EC50=72 μM).
  • HY-N4299
    Caesappanin C 1913319-59-1
    Caesappanin C, a biphenyl dimer from the ethanolic extract of the heartwood of Indonesian Caesalpinia sappan L., shows strong proliferation stimulating activity against the primary osteoblastic cells in vitro. Caesappanin C has the potential to stimulate bone formation and regeneration.
    Caesappanin C
  • HY-59001
    Sappanchalcone 94344-54-4
    Sappanchalcone, a flavonoid isolated from Caesalpinia sappan L., induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells.