1. Apoptosis
  2. Apoptosis
  3. Protosappanin B

Protosappanin B (Synonyms: (-)-Protosappanin B)

Cat. No.: HY-N0800
Handling Instructions

Protosappanin B is a phenolic compound extracted from Lignum Sappan. Anti-cancer activity. Protosappanin B induces apoptosis and causes G1 cell cycle arrest in human bladder cancer cells.

For research use only. We do not sell to patients.

Protosappanin B Chemical Structure

Protosappanin B Chemical Structure

CAS No. : 102036-29-3

Size Stock
1 mg   Get quote  
5 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Top Publications Citing Use of Products
  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Protosappanin B is a phenolic compound extracted from Lignum Sappan. Anti-cancer activity[1]. Protosappanin B induces apoptosis and causes G1 cell cycle arrest in human bladder cancer cells[2].

IC50 & Target

Apoptosis[2]

In Vitro

Protosappanin B (12.5, 25, 50, 100, 200 µg/mL, 48 hours) dose-dependently inhibits tumor cells, with IC50s of 21.32 µg/mL, 26.73 µg/mL, and 76.53 µg/mL for SW-480, HCT-116, and BTT cells, respectively[1].

Cell Viability Assay[1]

Cell Line: CT-116, SW-480, and BTT Cells
Concentration: 12.5, 25, 50, 100, 200 µg/mL
Incubation Time: 48 hours
Result: Dose-dependently inhibited tumor cells after 48 hours of treatment.
References
Molecular Weight

304.29

Formula

C₁₆H₁₆O₆

CAS No.

102036-29-3

SMILES

OC1=CC=C2C(OC[[email protected]@](O)(CO)CC3=CC(O)=C(O)C=C23)=C1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Protosappanin B
Cat. No.:
HY-N0800
Quantity:

Protosappanin B

Cat. No.: HY-N0800