PNU-282987 S enantiomer free base

Cat. No.: HY-12560D Purity: 99.58%: Data Sheet
COA

SDS
Handling Instructions
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PNU-282987 S enantiomer free base is the S-enantiomer of PNU-282987 free base. PNU-282987 is an α7 nicotinic acetylcholine receptor (α7 nAChR) agonist.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

PNU-282987 S enantiomer free base 화학구조

CAS No. : 737727-12-7

사이즈	재고	수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	해외재고보유	Estimated Time of Arrival: December 31
Solid
1 mg	해외재고보유	Estimated Time of Arrival: December 31
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	견적 받기
100 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Other Forms of PNU-282987 S enantiomer free base:

PNU-282987 In-stock
PNU-282987 free base 견적 받기
(S)-PNU-282987 hydrochloride 견적 받기

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

PNU-282987 S enantiomer free base is the S-enantiomer of PNU-282987 free base. PNU-282987 is an α7 nicotinic acetylcholine receptor (α7 nAChR) agonist.

분자량

264.75

화학식

C₁₄H₁₇ClN₂O

CAS No.

737727-12-7

Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC=C(Cl)C=C1)N[C@H]2C3CCN(CC3)C2

선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	2 years
	-20°C	1 year

용액&용해도

In Vitro:

DMSO : 100 mg/mL (377.71 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.7771 mL	18.8857 mL	37.7715 mL
5 mM	0.7554 mL	3.7771 mL	7.5543 mL
10 mM	0.3777 mL	1.8886 mL	3.7771 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

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Working solution concentration: mg/mL

순도&문서

Purity: 99.58%

Select Batch:

Data Sheet (269 KB) SDS (393 KB)

COA (248 KB) LCMS (120 KB)

Handling Instructions (2659 KB)

References

[1]. Bodnar AL, et al. Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors. J Med Chem. 2005 Feb 24;48(4):905-8. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.7771 mL	18.8857 mL	37.7715 mL	94.4287 mL
	5 mM	0.7554 mL	3.7771 mL	7.5543 mL	18.8857 mL
	10 mM	0.3777 mL	1.8886 mL	3.7771 mL	9.4429 mL
	15 mM	0.2518 mL	1.2590 mL	2.5181 mL	6.2952 mL
	20 mM	0.1889 mL	0.9443 mL	1.8886 mL	4.7214 mL
	25 mM	0.1511 mL	0.7554 mL	1.5109 mL	3.7771 mL
	30 mM	0.1259 mL	0.6295 mL	1.2590 mL	3.1476 mL
	40 mM	0.0944 mL	0.4721 mL	0.9443 mL	2.3607 mL
	50 mM	0.0755 mL	0.3777 mL	0.7554 mL	1.8886 mL
	60 mM	0.0630 mL	0.3148 mL	0.6295 mL	1.5738 mL
	80 mM	0.0472 mL	0.2361 mL	0.4721 mL	1.1804 mL
	100 mM	0.0378 mL	0.1889 mL	0.3777 mL	0.9443 mL