1. Membrane Transporter/Ion Channel
    Neuronal Signaling
    GPCR/G Protein
  2. nAChR
    5-HT Receptor
  3. PNU-282987 free base

PNU-282987 free base 

Cat. No.: HY-12560
Handling Instructions

PNU-282987 (free base) (Compound C7) is a potent α7 nicotinic acetylcholine receptor (nAChR) agonist with an EC50 of 154 nM. PNU-282987 (free base) is also a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM.

For research use only. We do not sell to patients.

PNU-282987 free base Chemical Structure

PNU-282987 free base Chemical Structure

CAS No. : 711085-63-1

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Description

PNU-282987 (free base) (Compound C7) is a potent α7 nicotinic acetylcholine receptor (nAChR) agonist with an EC50 of 154 nM. PNU-282987 (free base) is also a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM[1].

IC50 & Target

5-HT3 Receptor

 

Molecular Weight

264.75

Formula

C14H17ClN2O

CAS No.
SMILES

O=C(N[[email protected]]1CN2CCC1CC2)C3=CC=C(Cl)C=C3

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
PNU-282987 free base
Cat. No.:
HY-12560
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