711085-63-1
711085-63-1
Chemical Structure
PNU-282987 free base
- CAS No.: 711085-63-1
- Formula:C14H17ClN2O
- Molecular Weight:264.75
IUPAC Name: (R)-4-chloro-N-(quinuclidin-3-yl)benzamide
InChIKey: WECKJONDRAUFDD-ZDUSSCGKSA-N
SMILES: O=C(N[C@H]1CN2CCC1CC2)C3=CC=C(Cl)C=C3
Biological Activity: PNU-282987 (free base) is a potent α7 nicotinic acetylcholine receptor (nAChR) agonist with an EC50 of 154 nM. PNU-282987 (free base) is also a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM. PNU-282987 (free base) can be used for the research of central and peripheral nervous systems[1].
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PNU-282987 free base | PNU-282987 (free base) is a potent α7 nicotinic acetylcholine receptor (nAChR) agonist with an EC50 of 154 nM. PNU-282987 (free base) is also a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM. PNU-282987 (free base) can be used for the research of central and peripheral nervous systems. | |||||||||||||||||||||
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