PNU-282987 S enantiomer free base

Art. -Nr.: HY-12560D Reinheit: 99.58%: Data Sheet
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PNU-282987 S enantiomer free base is the S-enantiomer of PNU-282987 free base. PNU-282987 is an α7 nicotinic acetylcholine receptor (α7 nAChR) agonist.

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PNU-282987 S enantiomer free base Chemische Struktur

CAS. Nr. : 737727-12-7

Größe	Verfügbarkeit	Menge
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	Auf Lager	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	Auf Lager	Estimated Time of Arrival: December 31
Solid
1 mg	Auf Lager	Estimated Time of Arrival: December 31
5 mg	Auf Lager	Estimated Time of Arrival: December 31
10 mg	Auf Lager	Estimated Time of Arrival: December 31
50 mg	Angebot einholen
100 mg	Angebot einholen

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This product is a controlled substance and not for sale in your territory.

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Other Forms of PNU-282987 S enantiomer free base:

PNU-282987 In-stock
PNU-282987 free base Angebot einholen
(S)-PNU-282987 hydrochloride Angebot einholen

Spezialitätsempfehlungen

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

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Beschreibung

PNU-282987 S enantiomer free base is the S-enantiomer of PNU-282987 free base. PNU-282987 is an α7 nicotinic acetylcholine receptor (α7 nAChR) agonist.

Molekulargewicht

264.75

Formel

C₁₄H₁₇ClN₂O

CAS. Nr.

737727-12-7

Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC=C(Cl)C=C1)N[C@H]2C3CCN(CC3)C2

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	2 years
	-20°C	1 year

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 100 mg/mL (377.71 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.7771 mL	18.8857 mL	37.7715 mL
5 mM	0.7554 mL	3.7771 mL	7.5543 mL
10 mM	0.3777 mL	1.8886 mL	3.7771 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Molaritätsrechner
Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

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Working solution concentration: mg/mL

Reinheit & Dokumentation

Purity: 99.58%

Select Batch:

Data Sheet (269 KB) SDS (393 KB)

COA (248 KB) LCMS (120 KB)

Handling Instructions (2659 KB)

Verweise

[1]. Bodnar AL, et al. Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors. J Med Chem. 2005 Feb 24;48(4):905-8. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.7771 mL	18.8857 mL	37.7715 mL	94.4287 mL
	5 mM	0.7554 mL	3.7771 mL	7.5543 mL	18.8857 mL
	10 mM	0.3777 mL	1.8886 mL	3.7771 mL	9.4429 mL
	15 mM	0.2518 mL	1.2590 mL	2.5181 mL	6.2952 mL
	20 mM	0.1889 mL	0.9443 mL	1.8886 mL	4.7214 mL
	25 mM	0.1511 mL	0.7554 mL	1.5109 mL	3.7771 mL
	30 mM	0.1259 mL	0.6295 mL	1.2590 mL	3.1476 mL
	40 mM	0.0944 mL	0.4721 mL	0.9443 mL	2.3607 mL
	50 mM	0.0755 mL	0.3777 mL	0.7554 mL	1.8886 mL
	60 mM	0.0630 mL	0.3148 mL	0.6295 mL	1.5738 mL
	80 mM	0.0472 mL	0.2361 mL	0.4721 mL	1.1804 mL
	100 mM	0.0378 mL	0.1889 mL	0.3777 mL	0.9443 mL