1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. nAChR
  3. Lobeline hydrochloride

Lobeline hydrochloride (Synonyms: α-Lobeline hydrochloride; L-Lobeline hydrochloride)

Cat. No.: HY-B0979 Purity: 99.95%
Handling Instructions

Lobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes.

For research use only. We do not sell to patients.

Lobeline hydrochloride Chemical Structure

Lobeline hydrochloride Chemical Structure

CAS No. : 134-63-4

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Solution
10 mM * 1 mL in Water USD 61 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 61 In-stock
Estimated Time of Arrival: December 31
Solid
50 mg USD 55 In-stock
Estimated Time of Arrival: December 31
100 mg USD 99 In-stock
Estimated Time of Arrival: December 31
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Description

Lobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes.

Clinical Trial
Molecular Weight

373.92

Formula

C₂₂H₂₈ClNO₂

CAS No.
SMILES

CN1[[email protected]@H](CC(C2=CC=CC=C2)=O)CCC[[email protected]]1C[[email protected]](O)C3=CC=CC=C3.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

H2O : 6 mg/mL (16.05 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6744 mL 13.3718 mL 26.7437 mL
5 mM 0.5349 mL 2.6744 mL 5.3487 mL
10 mM 0.2674 mL 1.3372 mL 2.6744 mL
*Please refer to the solubility information to select the appropriate solvent.

Purity: 99.97%

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Keywords:

Lobelineα-LobelineL-LobelinenAChRNicotinic acetylcholine receptorsInhibitorinhibitorinhibit

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Lobeline hydrochloride
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HY-B0979
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